In 1989, Tilley was diagnosed with lymphatic cancer which she overcame.[2] Earlier that same year, she also opened a shop in the King's Gallery in Brussels.[1] She had various clothing collections, including Back Lines, a collection with wedding and party clothes and Inner & Earthings, a ready-to-wear women's collection. In addition, there was the Escape line, a collection that was released in a cheaper fabric, Jersey, and design.[3] In 1993, she designed the costumes for the film Antoine. Her children's line Frederiek was launched in 1995. This children's collection is named after her father, as the collection was launched shortly after her father's death. This children's collection was also sold in Galeries Lafayette in Paris.[4] In addition, she had her first show at the Parisian prêt-à-porter week in 1997.[3]
Tilley not only designed clothing, she also entered into a collaboration with Ad Lumen. For this, she designed her first lighting collection that matched the style of her clothing. The lamps were characterized by expressive and flowing lines. The lamps are made of copper and stainless steel. The glass for the lamps was mouth-blown, which ensured that they were always unique and different in shape. The copper was given an intense red color in different shades by heating, where there is no uniformity and depth was created. The lighting collection was part of a new way of working by Ad Lumen. They called on designers who have nothing to do with design and lighting.[5] In addition, she also created a Fashion room for the Royal Windsor hotel, characterized by a chalky white color.[4] In the meantime, she became an established name, as evidenced by the retrospective exhibition organized in the Gaasbeek Castle in 2005. Her new winter collection was inspired by the last resident of the castle; Marchioness Arconati Visconti.[4]
In 2007, Tilley collaborated again with a brand outside the fashion scene. She was asked to embellish the Elnett hairspray spray can by L’Oréal with a drawing. She wanted to show a sophisticated, exceptionally feminine but above all liberated woman in her design.[6] From 2007 onwards, Tilley organized exhibitions/experiences on her domain, a former water mill, in Asbeek (Asse).[7] During these events, her creations were exhibited, but prototypes and paintings of hers were also sold. In 2009, the central theme of this exhibition/experience was Albino. While the exhibitions of the previous two years were mainly retrospective, in 2009 she showed exclusively new creations.[8]
After the bankruptcy of her shops in Brussels and Antwerp in 2009, a relaunch was started after two years. Under the name Salon de Rencontre Belle Boudoir, a complete experience world/experience was created. Tilley wanted to offer party and bridal wear, jewelry, the children's collection, lighting and furniture at an exclusive room level.[9] In the salons, a permanent collection was for sale, with new creations added every month that were organized thematically. The clothing was handmade and could be made to measure.[9]