Sedky was a long-term vice president of the Egyptian National Bar.[3] He was named as the head of the Bar in 1936.[2] He was also a long-term member of the Coptic Community Council where he served until 1942.[3] He was made a senator and was part of the Egyptian delegations in the International Parliamentary Congresses held in 1928 and in 1930.[3]
Sedky joined the Wafd Party on 2 December 1932.[3] He was made the vice president of the Egyptian Parliament in 1934.[3] He was appointed minister of commerce and industry in February 1942 to the cabinet led by Mostafa El Nahas.[3] Sedky was also named as the minister of finance in May 1942 when Makram Ebeid was removed from office.[3] On the same date Sedky was awarded with the title Pasha.[3] His both ministerial tenures ended in June 1943.[3] Then he was appointed president of the State Audit on 2 June 1943.[2] His succeeded Amin Osman in the post who in turn, succeeded Sedky as minister of finance.[2] Sedky headed the State Audit until his retirement on 1 March 1945.[2]