Kappadione

Kappadione is a vitamin K derivative used for the treatment of side effects of vitamin K antagonists such as warfarin, prophylaxis and treatment of vitamin K deficiency bleeding, and hypoprothrombinemia due to various causes.^[1] It was manufactured by Eli Lilly and Company.^[2] Chemically, it is menadiol sodium diphosphate. It was approved by the US Food and Drug Administration prior to 1982 and marketed by Lilly. It has since been discontinued and is not available in North America.^[1]

Routes of
administrationInjection

ATC code

• none

Legal status

• US: Rx only, discontinued (was FDA approved)
• In general: ℞ (Prescription only)

CAS Number

• 6700-42-1 ^Y

Quick facts Clinical data, Routes ofadministration ...

Kappadione

Clinical data
Routes of administration	Injection
ATC code	none
Legal status
Legal status	US: Rx only, discontinued (was FDA approved) In general: ℞ (Prescription only)
Identifiers
IUPAC name Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate
CAS Number	6700-42-1 Y
PubChem CID	8555
DrugBank	DB09332 Y
ChemSpider	8237 N
UNII	2OVL75B30W
KEGG	D04908
CompTox Dashboard (EPA)	DTXSID80156832
ECHA InfoCard	100.004.558
Chemical and physical data
Formula	C11H8Na4O8P2
Molar mass	422.084 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(C2=CC=CC=C2C(=C1)OP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]
InChI InChI=1S/C11H12O8P2.4Na/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17;;;;/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17);;;;/q;4*+1/p-4 N Key:GZBACHSOZNEZOG-UHFFFAOYSA-J N
NY (what is this?)  (verify)

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