Ketipramine

Ketipramine (G-35,259), also known as ketimipramine or ketoimipramine, is a tricyclic antidepressant (TCA) that was tested in clinical trials for the treatment of depression in the 1960s but was never marketed.^[1][2][3] It differs from imipramine in terms of chemical structure only by a single ketone group, and is approximately equivalent in effectiveness as an antidepressant in comparison.^[4]

Routes of
administrationOral

ATC code

• none

CAS Number

• 796-29-2 ^Y
• Fumarate salt: 17243-32-2 ^Y

PubChem CID

• 28424

Quick facts Clinical data, Routes ofadministration ...

Ketipramine

Clinical data
Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name 5-[3-(dimethylamino)propyl]-5,11-dihydro-10H-dibenzo[b,f]azepin-10-one
CAS Number	796-29-2 Y Fumarate salt: 17243-32-2 Y
PubChem CID	28424
ChemSpider	26443
UNII	U5C4H63K5U Fumarate salt: 86490E9X8J Y
CompTox Dashboard (EPA)	DTXSID60229790
Chemical and physical data
Formula	C19H22N2O
Molar mass	294.398 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C3c1c(cccc1)N(c2c(cccc2)C3)CCCN(C)C

Close

It was one of the drugs tested by Roland Kuhn in a series of unethical experiments testing drugs on children without informed consent that were done in a psychiatric hospital located in Münsterlingen, Switzerland.^[5][6][7]