Sanie realized her calling to help others at a young age and had always wanted to start a charity since childhood, speaking about it as early as primary school. While still in her first year of high school at Wesley Girls' High School, she and some friends started a project to help needy children.[4] This small charity eventually grew into a fully structured and registered NGO called For The Future (FTF) Ghana,[5] where majority of the pioneers and members are students in various universities in Ghana.[6][7]
Through her work with FTF Ghana, Kezia has led initiatives that have impacted over 5,000 children across Ghana and Nigeria.[8] The organization has renovated a school block, provided teaching and learning materials to over 3000 vulnerable children, and increased access to education and quality healthcare to numerous underprivileged children across the country.[6]
On Friday, August 11, 2023, Kezia was sworn in as the youngest member of the 13-member board of trustees for the Head of State Awards Scheme at the Jubilee House in Accra by President Nana Addo Dankwa Akufo-Addo.[9]
The Head of State Award Scheme (also known globally as the Duke of Edinburgh’s International Award) is a non-formal education and learning program that challenges, empowers, and recognizes young people aged 14 to 24.[10]
Other members of the board include Harry B. Sintim-Aboagye (chairman), Gladys Amoah (vice-chairman), Kwadwo Addeah-Safo (secretary), Daniel A Adotey, Hajia Muniratu Lamptey, Dr Juliet Yayra Tengey, Ohenewa Sakyi Bekoe, Stephen Oduro, Pius Enam Hadzide, Gifty Sakyi-Bremansu, Abena A Antwi, and Peter A. Anum (chief executive).[11]
In May 2025, she will join the 54th St. Gallen Symposium as a speaker.[12]