Krishna Chatterjee

Chatterjee was born on 23 April 1958. He was educated at Wolfson College, Oxford, where he was awarded a Bachelor of Arts degree, and a Bachelor of Medicine, Bachelor of Surgery degree in 1982.^[1][5]

Chatterjee is distinguished for his discoveries of genetic disorders of thyroid gland formation, regulation of hormone synthesis and hormone action, which have advanced fundamental knowledge of the hypothalamic–pituitary–thyroid axis.^[6] He has identified dominant negative inhibition by defective nuclear receptors as a common mechanism in thyroid hormone resistance and peroxisome proliferator-activated receptor gamma (PPARγ)-mediated insulin resistance.^[6][7] He has shown how deficiency of human selenocysteine-containing proteins causes a multisystem disease, including disordered thyroid hormone metabolism. He seeks to translate such understanding into better diagnosis and therapy of both rare and common thyroid conditions.^[6]

Notable Cambridge scientists with whom Chatterjee has shared paper authorship include Sadaf Farooqi, Stephen O'Rahilly, Antonio Vidal-Puig, and Nick Wareham.

Chatterjee was appointed Commander of the Order of the British Empire (CBE) in the 2023 New Year Honours for services to people with endocrine disorders.^[8]