As a freshman at New Mexico State in 2016, Bradish appeared in 17 games (15 starts) in which he compiled an 8–3 record with a 4.67 ERA, striking out a team-high 82 batters over 86+2⁄3 innings.[4] In 2017, his sophomore season, he went 8–2 with a 3.20 ERA over 15 games (14 starts), and was named to the Western Athletic Conference First-Team.[5][6] That summer, he played for the Falmouth Commodores of the Cape Cod Baseball League, and was named an All-Star.[7][8] As a junior in 2018, he went 9–3 with a 2.67 ERA over 17 starts, and was named to the All-WAC Team for the second straight season.[9][10]
On November 19, 2021, the Orioles selected Bradish's contract and added him to their 40-man roster in order to protect him from the Rule 5 draft.[19] He returned to Norfolk to open the 2022 season.[20] On April 29, 2022, the Orioles promoted Bradish to the majors to make his MLB debut that night as the starting pitcher versus the Boston Red Sox.[21] Bradish allowed two earned runs over six innings pitched while striking out two batters and walking one in his debut.[22] On May 10, Bradish earned his first career win against the St. Louis Cardinals, at one point retiring 11 consecutive batters.[23]
On September 22, 2022, Bradish allowed just two hits to the Houston Astros over 8+2⁄3 innings to lead an Orioles' shutout of the Astros, 2–0. He struck out ten in the longest outing to-date of his professional career.[24] He finished the 2022 season with a 4–7 record and a 4.90 ERA which was 3.28 after the All-Star break.[25]
Bradish began the 2023 season as the Orioles number four pitcher in the rotation. He was pulled after only 1+2⁄3 innings in his first start of the season after taking a line drive off his foot. He would return to the Orioles rotation 16 days later, after a stint on the 15-Day IL with a right foot contusion. He pitched six scoreless innings against the Washington Nationals, striking out six batters and earning his first win of the season.[citation needed] Bradish finished the regular season with a 12–7 record in 30 starts, pitching 168+2⁄3 innings with 168 strikeouts. His 2.83 ERA was the fourth-best in the Majors and his 1.04 WHIP was third-best in the league. He ended the season as the ace of the Orioles starting rotation, having been assigned a Game 1 playoff start against the Texas Rangers.[26]
On February 15, 2024, general manager Mike Elias announced that Bradish was diagnosed with a sprain in the ulnar collateral ligament of his right elbow and would begin the season on the injured list.[27] He was activated on May 2.[28] In 8 starts for the Orioles, Bradish compiled a 2.75 ERA with 53 strikeouts across 39+1⁄3 innings pitched. On June 19, it was announced that Bradish had undergone Tommy John surgery, ending his season.[29]
On August 26, 2025, Bradish was activated from the injured list to make his season debut and return from surgery.[30] He earned his first win in fifteen months in a 4–1 away victory over the Chicago White Sox on 15 September, his fourth start since returning from the injured list.[31][32]
