L-arabinitol 4-dehydrogenase
From Wikipedia, the free encyclopedia
In enzymology, a L-arabinitol 4-dehydrogenase (EC 1.1.1.12) is an enzyme that catalyzes the chemical reaction
| L-arabinitol 4-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 L-arabinitol 4-dehydrogenase homotetramer, Neurospora crassa | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.1.12 | ||||||||
| CAS no. | 9028-19-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The two substrates are L-arabinitol and oxidised nicotinamide adenine dinucleotide (NAD+). The products are L-xylulose, reduced cofactor NADH, and a proton.[1]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.[2][3]
