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LARP4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

La-related protein 4 is a protein that in humans is encoded by the LARP4 gene.[4][5] LARP4 is an RNA-binding protein which consists of a La motif (LaM), RNA recognition motif (RRM) and a putative PABP binding motif. It has been shown that LARP4 is involved in mRNA stability.[6]

AliasesLARP4, PP13296, La ribonucleoprotein domain family member 4
External IDsMGI: 2443114; GeneCards: LARP4
PDBOrtholog search: PDBe RCSB
Chr.Chromosome 15 (mouse)[1]
Quick facts Identifiers, Aliases ...
LARP4
Identifiers
AliasesLARP4, PP13296, La ribonucleoprotein domain family member 4
External IDsMGI: 2443114; GeneCards: LARP4
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001024526
NM_001080948
NM_001284521
NM_001284522
NM_001284523

RefSeq (protein)

NP_001019697
NP_001074417
NP_001271450
NP_001271451
NP_001271452

Location (UCSC)n/aChr 15: 99.87 – 99.91 Mb
PubMed search[2][3]
Wikidata
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LARP4 is known to regulate cancer cell migration and invasion by altering cell shape.[7] It is also reported to be a glioma tumor suppressor.[8]

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