LETM1-like protein family
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| LETM1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | LETM1 | ||||||||
| Pfam | PF07766 | ||||||||
| InterPro | IPR011685 | ||||||||
| TCDB | 8.A.20 | ||||||||
| |||||||||
LETM1-like is a family of evolutionarily related proteins. This is a group of mainly hypothetical eukaryotic proteins. Putative features found in LETM1, such as a transmembrane domain and a CK2 and PKC phosphorylation site,[1] are relatively conserved throughout the family. Deletion of LETM1 is thought to be involved in the development of Wolf-Hirschhorn syndrome in humans.[1] A member of this family, SWISSPROT, is known to be expressed in the mitochondria of Drosophila melanogaster,[2] suggesting that this may be a group of mitochondrial proteins.