LHX3

LHX3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JTN, 2RGT
Identifiers
Aliases	LHX3, CPHD3, LIM3, M2-LIM homeobox 3
External IDs	OMIM: 600577; MGI: 102673; HomoloGene: 7814; GeneCards: LHX3; OMA:LHX3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,205,128 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	26,098,301 bp
RNA expression pattern
	Top expressed in
	pituitary gland; ; anterior pituitary; ; pancreatic ductal cell; ; tibialis anterior muscle; ; popliteal artery; ; testicle; ; Epithelium of choroid plexus; ; optic nerve; ; islet of Langerhans; ; nucleus of brain;
	Top expressed in
	Rathke's pouch; ; pituitary gland; ; pars intermedia; ; vestibular sensory epithelium; ; pineal gland; ; pars distalis of adenohypophysis; ; embryo; ; neural layer of retina; ; utricle; ; pretectal area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	transcription regulator complex; intracellular anatomical structure; nucleus;
Biological process	ventral spinal cord interneuron specification; cell differentiation; pituitary gland development; regulation of transcription, DNA-templated; spinal cord association neuron differentiation; spinal cord motor neuron cell fate specification; placenta development; lung development; negative regulation of apoptotic process; transcription, DNA-templated; positive regulation of transcription, DNA-templated; animal organ morphogenesis; inner ear development; medial motor column neuron differentiation; motor neuron axon guidance; dorsal/ventral pattern formation; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; neuron differentiation;
	Sources:Amigo / QuickGO
Orthologs
	8022
	16871
	ENSG00000107187
	ENSMUSG00000026934
	Q9UBR4
	P50481
	NM_014564; NM_178138; NM_001363746
	NM_001039653; NM_010711
	NP_055379; NP_835258; NP_001350675
	NP_001034742; NP_034841
	Wikidata
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