LMX1B
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene.[5][6]
External IDsOMIM: 602575; MGI: 1100513; HomoloGene: 55648; GeneCards: LMX1B; OMA:LMX1B - orthologs
Function
LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb.[7]
Clinical significance
Loss-of-function mutations in the LMX1B gene are associated with Nail-patella syndrome.[8]