Lafadofensine

Lafadofensine (INNTooltip International Nonproprietary Name), also known as (3S)-N,N-bis(4-fluorophenyl)pyrrolidin-3-amine, is a drug described as an antidepressant which has not been marketed at this time.^[1][2][3] It is said to act as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI).^[1] The drug was first described by 2010^[4] and its INNTooltip International Nonproprietary Name was proposed by 2021.^[5]

Drug classSerotonin–norepinephrine–dopamine reuptake inhibitor

CAS Number

• 914989-90-5
  914989-91-6 (fumarate)

PubChem CID

• 15605612

ChemSpider

• 13081085

Quick facts Clinical data, Drug class ...

Lafadofensine

Clinical data
Drug class	Serotonin–norepinephrine–dopamine reuptake inhibitor
Identifiers
IUPAC name (3S)-N,N-bis(4-fluorophenyl)pyrrolidin-3-amine
CAS Number	914989-90-5 914989-91-6 (fumarate)
PubChem CID	15605612
ChemSpider	13081085
UNII	7HFV4D3KJL
ChEMBL	ChEMBL5095070
Chemical and physical data
Formula	C16H16F2N2
Molar mass	274.315 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CNC[C@H]1N(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
InChI InChI=1S/C16H16F2N2/c17-12-1-5-14(6-2-12)20(16-9-10-19-11-16)15-7-3-13(18)4-8-15/h1-8,16,19H,9-11H2/t16-/m0/s1 Key:ZKEVVJGPWXTETN-INIZCTEOSA-N

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