In 1902 Aguirre wrote to President Theodore Roosevelt to request protection as a political refugee, after having heard a rumor that the Díaz government planned to kidnap him.[1] The previous year, the mayor of Ciudad Juárez had complained to United States authorities about subversive activities by Aguirre associated with his newspaper, which had been renamed El Progresista.[1] The U.S. consul charged with investigating Aguirre's complaint found no evidence of a kidnapping plot.[1]
Afterward Aguirre launched another newspaper, La Reforma Social, and joined the Partido Liberal Mexicano (PLM), which was the most extreme of the anti-Díaz organizations.[1] Aguirre became president of the El Paso PLM branch and organized an attempted takeover of Ciudad Juárez.[1] Their plans failed because Díaz government agents infiltrated the PLM.[1] Enrique C. Creel, the governor of Chihuahua, attempted to get Aguirre extradited in 1906 by framing him for murder and having Mexican officials present forged evidence to American officials.[2] Aguirre was arrested and jailed in the United States for forty days before evidence of his innocence prompted his release.[2]
Aguirre continued to publish about Mexican politics with another newspaper, El Precursor. He retired in 1913.[2]