Lawrence A. Loeb
From Wikipedia, the free encyclopedia
Bellevue Hospital Medical College (MD, 1961)
University of California, Berkeley (PhD, 1967)
Genetics
Cancer
DNA sequencing
Lawrence A. Loeb | |
|---|---|
 Loeb in 2009 | |
| Born | December 25, 1936 Poughkeepsie, New York, United States |
| Alma mater | City College of New York (BS , 1957) Bellevue Hospital Medical College (MD, 1961) University of California, Berkeley (PhD, 1967) |
| Scientific career | |
| Fields | Genomics Genetics Cancer DNA sequencing |
| Institutions | Institute for Cancer Research University of Washington |
Lawrence A. "Larry" Loeb is an American cancer researcher and genome scientist. He is a professor of pathology and biochemistry at the University of Washington. Loeb is best known for his work on the fidelity of DNA polymerase, and his proposal of the mutator phenotype hypothesis in cancers.
Loeb was born in Poughkeepsie, New York.[1] He enrolled in the City College of New York at age 17, earning his bachelor's degree in 1957.[1] In 1958, he matriculated at Bellevue Hospital Medical College earning his medical doctorate three years later.[1] Loeb completed his medical internship at Stanford University from 1961 to 1962.[1]
Loeb left medical practice for scientific research, serving as a research associate with Harry V. Gelboin at the National Cancer Institute from 1962 to 1964.[1] He then resumed work as a research associate with Daniel Mazia at the University of California, Berkeley, and ultimately earned a PhD in biochemistry in 1967.[1]
Loeb worked at the Institute for Cancer Research (now Fox Chase Cancer Center) from 1967 to 1978 before accepting a faculty position at the University of Washington department of Pathology in 1978, as Director of The Joseph Gottstein Memorial Cancer Research Laboratory.[1][2] Loeb remained at the University of Washington until his retirement in 2023.[1]
Loeb has served as President of the American Association for Cancer Research and the Environmental Mutagen Society, and on the board of directors for the American Association for Cancer Research.[3] He also served as director of the University of Washington Medical Scientist Training Program from 1986 to 2011.[1]