Legonmycin

Group of chemical compounds From Wikipedia, the free encyclopedia

Legonmycins are a group of chemical compounds that belong to the pyrrolizidine family of naturally occurring alkaloids. Discovered by a joint team of researchers from University of Ghana, University of Aberdeen, and Wuhan University, the compounds were isolated from Streptomyces microorganisms in Legon, a suburb of Accra, Ghana.[1][2][3][4] Laboratory syntheses of legonmycin A and legonmycin B have been reported.[5]

Quick facts Names, Identifiers ...
Legonmycin
Legonmycin A (top) and legonmycin B
Names
IUPAC names
A: N-(8-Hydroxy-2-methyl-1-oxo-6,7-dihydro-5H-pyrrolizin-3-yl)-3-methylbutanamide
B: N-(8-Hydroxy-2-methyl-1-oxo-6,7-dihydro-5H-pyrrolizin-3-yl)-4-methylpentanamide
Identifiers
3D model (JSmol)
ChemSpider
  • A: InChI=1S/C13H20N2O3/c1-8(2)7-10(16)14-12-9(3)11(17)13(18)5-4-6-15(12)13/h8,18H,4-7H2,1-3H3,(H,14,16)
    Key: PLSCDSCQUZWYJL-UHFFFAOYSA-N
  • B: InChI=1S/C14H22N2O3/c1-9(2)5-6-11(17)15-13-10(3)12(18)14(19)7-4-8-16(13)14/h9,19H,4-8H2,1-3H3,(H,15,17)
    Key: STVITZBETCSTPL-UHFFFAOYSA-N
  • A: CC1=C(N2CCCC2(C1=O)O)NC(=O)CC(C)C
  • B: CC1=C(N2CCCC2(C1=O)O)NC(=O)CCC(C)C
Properties
A: C13H20N2O3
B: C14H22N2O3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References

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