Lezanne Ooi
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University of York
University of Leeds
Lezanne Ooi | |
|---|---|
| Alma mater | University of Leeds University of York |
| Known for | Neuroscience |
| Scientific career | |
| Institutions | University of Wollongong University of Leeds |
| Thesis | An analysis of repressor element 1- silencing transcription factor interactions with its target genes (2005) |
Lezanne Ooi is an Australian neuroscientist who is Professor and Head of Neurodevelopment at the University of Wollongong. Her research considers the development of cellular imaging techniques to understand neurodegenerative disease.
Ooi trained in the United Kingdom. She studied biochemistry at the University of York, where she worked with GlaxoSmith Kline.[1] When Ooi was studying neuroscience, her grandmother was diagnosed with dementia, which motivated her to purse a career studying neurodegenerative disease.[2][3] She completed her doctoral research on the transcriptional repressor REST (Repressor Element 1-Silencing Transcription factor) at the University of Leeds.[1][4] She remained there as a postdoctoral researcher, where she studied cardiac hypertrophy and developed cellular imaging techniques to understand neuronal function.[1] Her research showed that atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) became abnormally high in people with hypertrophy, and that an increase in REST could halt the rise of the other proteins.[5]
