Lipoate–protein ligase
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Lipoate–protein ligase (EC 2.7.7.63, LplA, lipoate protein ligase, lipoate–protein ligase A, LPL, LPL-B) is an enzyme with systematic name ATP:lipoate adenylyltransferase.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
- (1) ATP + lipoate diphosphate + lipoyl-AMP
- (2) lipoyl-AMP + apoprotein protein N6-(lipoyl)lysine + AMP
| Lipoate–protein ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.63 | ||||||||
| CAS no. | 144114-18-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme requires Mg2+ as a cofactor.
