List of The Nightly Show with Larry Wilmore episodes (2015)

Larry discusses the backlash over the Oscar nominations' lack of diversity and the success of recent protests. During the closing he pays tribute to Stephen Colbert for making the time slot special.

Larry takes an unflinching look at the sexual assault allegations against Bill Cosby.

Larry discusses the 2015 State of the Union Address as well as the image and legacy of President Obama.

Larry discusses the changing state of Cuba–United States relations.

Larry examines the controversy swirling around the movie American Sniper.

Larry talks about the Disneyland measles epidemic and the debate over vaccines.

Larry discusses the Koch brothers and the flood of private money in political campaigns.

Larry tackles the Deflategate scandal and dishonesty in professional sports.

Larry addresses America's growing obesity rate.

Larry compares the struggles of black people with the struggles of the LGBT community; and gay marriage in the United States.

Larry discusses the presence of black fathers in their kid's lives. The opening segment is omitted in favor of an extended panel discussion and additional "Keep it 100" questions.

Larry discusses the pros and cons of "designer babies".

Larry discusses war.

Larry discusses parenting.

The show is composed of questions asked by viewers for Larry and the panel regarding topics discussed in previous episodes. The opening segment is omitted in favor of an extended panel discussion.

Larry discusses Rudy Giuliani's claim that President Obama doesn't love America.

Larry examines Islamophobia and Muslim extremism.

Larry discusses the Mars One project, a one-way trip to Mars. Larry plays a game where he is a Martian asking the panel to describe earth things to him. Panelist Sonia Van Meter is a contender in actually participating in Mars One.

Larry discusses woman in the black community. The opening segment is omitted in favor of an extended panel discussion and additional "Keep it 100" questions.

Larry has a one-on-one discussion with New York Mayor Bill de Blasio.

Larry discusses allowing college students to carry guns on campus.

Larry discusses the legalization of marijuana.

Larry discusses the racial profiling in the Ferguson Police Department.

Larry ponders the moral ramifications of using technology made under hash working conditions.

Larry discusses the University of Oklahoma Sigma Alpha Epsilon racism incident, Larry and the panel discuss women's rights and leadership

Larry and the panel discuss political correctness and use of racist and sexist terms

Larry discusses the "Blurred Lines" plagiarism lawsuit, Larry and the panel discuss boxing and its effect on athletes

Larry discusses the discrimination of the LGBT community in New York City's annual Saint Patrick's Day parade.

Larry examines the race-based Starbucks campaign "Race Together".

Larry discusses Ted Cruz running in the 2016 presidential election.

Larry defines the word "slut", and discusses slut-shaming.

Before going on a break Larry dedicates the entire episode to several small stories, that alone wouldn't warrant an entire episode.

Larry discusses the Religious Freedom Restoration Act in Indiana, and debuts his new desk.

Larry discusses the treatment of food stamp recipients.

Larry discusses the shooting of Walter Scott and Rand Paul running in the 2016 presidential election.

Larry hosts the entire episode in a full spandex suit, as he promised as a result of the outcome of the "Dare-y Wilmore's March Badness Bracketsball Dare-O-Mania 2015 – It's Boner Time!" game. Larry also discusses the price of a college and ponders if college is even worth it in particular cases.

Larry discusses the 2016 presidential campaign for Hillary Clinton.

Larry discusses the fate of Dzhokhar Tsarnaev, who has been found guilty perpetrating the Boston Marathon bombings in 2013. Larry also discuses the usage of capital punishment in the United States. Panelist Alex Wagner had to leave early, and was replaced by audience member Linda Pacotti to participate in the game "Cool & Unusual".

Larry discusses the pros and cons of snitching on people. Mike Yard offers tax tips during his segment "Savin' Hard with Yard".

Larry examines various conspiracy theories.

Larry discusses Britt McHenry's publicly taped verbal abuse controversy, and Ben Affleck having references to his slave owning ancestors removed from his appearance on Finding Your Roots.

Larry discusses abrupt layoffs from Walmart, water being shut off for low income people in Baltimore, and a policeman who did not commit police brutality.

Larry discusses the water drought in California.

Larry discusses pastor Creflo Dollar trying to fund missionary trips to Mars and relationships between students and teachers.

Larry discusses Caitlyn Jenner's gender transition,^[a] and has Ian Harvie explain different gender identities to him.

Larry discuses the unfolding riots in Baltimore, and the media's coverage of them.

Larry discuses the new developments in the Baltimore riots and their media coverage, and Felonious Munk debuts to question the use of the word "thug".

Larry travels to a diner in Baltimore for a pre-taped out-of-studio interview with members of the Bloods and members of the Crips, who have called a truce with each other. Larry (back in the studio) then discusses a claim linking gay marriage to abortion. Later, with the panel, Larry hosts various short discussions about random topics chosen by the panelists from the "Bag of Grabs".

Larry discusses the developments in Baltimore and asks various science questions Bill Nye.

Larry discusses the holiday Cinco de Mayo, and the shootings at the Curtis Culwell Center, as backlash from an exhibition featuring works depicting Muhammad.