List of The Pitt characters

Cast overview

In decreasing order of seniority, the medical hierarchy begins with the attending physician, followed by senior residents, junior residents (categorized by year), interns (first-year residents), and finally, medical students (categorized by year). Nurses and other medical staff have their own hierarchy not listed here.

Key

  Main cast (receives star billing)

  Recurring cast (credited as guest starring in two or more episodes)

  Guest cast (credited as guest starring in one episode)

  Co-starring cast (credited as co-starring in one or more episodes)

Dr. Michael "Robby" Robinavitch

Dr. Michael "Robby" Robinavitch (Noah Wyle) is the longtime senior attending physician at the Pitt. He is a talented but sometimes reckless and irascible physician with a sharp wit and intense dedication to his patients and his team, which earns him the respect of the doctors and nurses, but often the ire of the hospital's administrators. Robby carries intense trauma from losing his mentor, Dr. Adamson, during the COVID-19 pandemic, and avoids working a shift on the anniversary of Adamson's death prior to the events of the first season.

In season 1, Robby arrives for a shift at the Pitt on the fourth anniversary of Adamson's death and spends the day leading an overcrowded, understaffed ER while clashing with hospital leadership over systemic problems. Robby is shattered to learn that Dr. Frank Langdon, his longtime protege, has been stealing benzodiazepenes from the hospital. After a local music festival mass shooting sends a wave of victims into the hospital, Robby helps lead the emergency response but is devastated when he cannot save Leah, the girlfriend of Jake Malloy, the son of his ex-girlfriend with whom he has a paternal bond. The trauma of the shooting and unresolved grief over Adamson's death culminate in Robby suffering a panic attack, but he ultimately returns to finish the shift and is later comforted by Dana and Jack Abbot.

In season 2, set ten months later on the Fourth of July, Robby begins what is meant to be his final shift before a three-month sabbatical he intends to spend riding a motorcycle cross-country, but quickly finds himself under pressure. He clashes with his interim replacement Dr. Baran Al-Hashimi, and remains distant and resentful toward Langdon (who returns after rehab). As the shift continues, Robby is deeply affected by several patients and repeatedly brushes off concerns about his increasingly erratic behavior, unresolved PTSD, and possible suicidal ideation driving his desire to take a sabbatical. His colleagues, including Dana, Abbot, McKay, as well as his motorcyclist friend Duke Ekins, grow alarmed as Robby spirals. Robby eventually admits to Duke that he is suicidal and that the hospital provides the only distraction from his thoughts. Both Abbot and Langdon urge Robby to seek help; Robby admits to Abbot that the constant death he witnesses on the job has taken a toll on his psyche and deprived him of the will to live, but Abbot reminds them of the value of their work and encourages Robby to take a safer trip than a motorcycle ride. Robby goes to check on a baby abandoned in the ER earlier that day and bonds with the child, with he himself having been abandoned by his mother when he was eight years old; Robby reassures the baby, and himself, that life has much left to offer.

Dr. Heather Collins

Dr. Heather Collins (Tracy Ifeachor) is a senior resident at the Pitt. She and Robby are former romantic partners who remain on good terms while working together, and she often grounds Robby's more reckless impulses.

In season 1, Collins works a chaotic shift in the ER while quietly hiding her pregnancy and trying to maintain her usual composure. She handles several major cases throughout the day, including Minu's traumatic leg injury, Otis Williams's cardiac collapse, Nick Bradley's overdose, and Hank Gaines's chest wound, while also teaching younger staff such as Javadi and Santos. She frequently clashes with Robby over medical judgment, ethics, and his tendency to overstep, but also shows lingering emotional intimacy with him. Collins later suffers a miscarriage; Robby comforts her, and she reveals she previously had an abortion, with Robby realizing the child was his. Robby tells her to forgive herself and encourages her to go home and turn off her phone, causing Collins to miss the mass casualty event at the ER following a shooting at a music festival.

In season 2, Collins is no longer at the Pitt, having completed her residency and moved back to Portland, Oregon, where she takes an attending position. Whitaker reveals that she left partly to be closer to family and because she is adopting a baby.

Dr. Frank Langdon

Dr. Frank Langdon (Patrick Ball) is a senior resident and Robby's trusted protege.

Dana Evans

Dana Evans (Katherine LaNasa) is the no-nonsense day-shift charge nurse.

Dr. Samira Mohan

Dr. Samira Mohan (Supriya Ganesh) is a third-year medical resident trying to find balance between diligence and speed.

Dr. Cassie McKay

Dr. Cassie McKay (Fiona Dourif) is a 42-year-old second-year resident raising her young son, Harrison, as a single mother.

Dr. Melissa "Mel" King

Dr. Melissa "Mel" King (Taylor Dearden) is a neurodivergent second-year resident with an autistic sister.

Dr. Trinity Santos

Dr. Trinity Santos (Isa Briones) is a cocky and ambitious intern.

Dr. Dennis Whitaker

Dr. Dennis Whitaker (Gerran Howell) is a gentle but naive fourth-year medical student.

Victoria Javadi

Victoria Javadi (Shabana Azeez) is a 20-year-old third-year medical student whose parents also work in medicine.

Dr. Baran Al-Hashimi

Dr. Baran Al-Hashimi (Sepideh Moafi) is a new attending physician at the Pitt who arrives as Robby's interim replacement ahead of his sabbatical. Al-Hashimi is shown having strange blackouts at several points. It is later revealed that Al-Hashimi has been living with a seizure disorder for 35 years after fighting viral meningitis as a child.

Dr. Jack Abbot

Dr. Jack Abbot (Shawn Hatosy) is a night shift attending physician at The Pitt. An old friend and confidant of Robby, Abbot is a former military doctor who served and was wounded overseas, as well as a widower. He also volunteers with the Pittsburgh Police as a SWAT Physician. Like Robby, Abbot often resorts to reckless and improvisational tactics to save patients, but is shown to be shrewd, highly competent, and charismatic, and credits therapy with helping him cope with the trauma of his past and his work as a physician.

Abbot is first seen standing at the edge of the roof at end of his shift, feeling despondent over the death of a patient who served in the military; Robby convinces him to return downstairs. Abbot later arrives early alongside several other night shift staff to help Robby and the day shift treat victims of a mass shooting at Pitt Fest, having received news of the incident via police scanner. Abbot's experience practicing combat-zone medicine proves invaluable during the mass casualty, with Abbot himself having brought several tools (such as portable ultrasound and cricothyrotomy kits) that expedite the staff's work when their resources are quickly depleted. At the end of the shift, Abbot finds Robby standing on the edge of the roof, reeling from the death of Leah, the girlfriend of his de facto stepson Jake, and feeling like a failure for having a panic attack during the shift; Abbot assures Robby that he performed excellently, and stresses the importance of their work, convincing Robby to leave with him. The two share beers in the park across from the hospital with other staff; Abbot is revealed to be an amputee, having lost his leg while serving in the military.

Abbot returns in season 2 midway through the day shift with an officer who was wounded during a SWAT raid, and helps Robby and his staff save him. Mohan helps Abbot bandage a minor wound he suffered during the raid, and tells Abbot about her patient, Orlando Diaz, who left the hospital against medical advice due to mounting medical debts; Abbot offers to personally pay for medical supplies to be delivered to Orlando's home via Uber. Abbot also assists in treating obese patient Howard Knox, and accompanies him to a neighboring hospital for scans before going home to rest prior to the night shift. Abbot returns for the night shift to serve as attending alongside Shen. He and Robby work together to save pregnant mother Judith Lastrade and her newborn after she suffers pre-eclampsia while attempting a freebirth. Afterwards, Abbot has an emotional conversation with Robby, who has become suicidal due to years of ignoring his mental health struggles while allowing the constant death he witnesses on the job to take a toll on him. Abbot stresses the importance of therapy, telling Robby that it helped him come to terms with the loss of his leg and later his wife, and recommends that Robby take a safer trip than riding a motorcycle helmetless.

Perlah Alawi

Perlah Alawi (Amielynn Abellera) is a nurse working in the ER. She is close with fellow nurse Princess Dela Cruz who, like her, is of Filipino ancestry, and the two are often heard gossiping with each other in Tagalog about the goings-on at the hospital. In season 2, Perlah is deeply shaken by the death of regular patient Louie Cloverfield, prompting Dana to take over for her in preparing Louie's body for viewing. She and Dana later share a tender embrace while watching the Fourth of July fireworks from the hospital's roof.

Mateo Diaz

Mateo Diaz (Jalen Thomas Brooks) is a nurse working in the ER. Javadi is instantly attracted to him upon meeting him and asks him out on a date that day, but he gently declines, telling her he does not date coworkers. He comes to admire Javadi over the course of their first shift together, especially when she improvises treatment plans under pressure during a mass casualty incident when the hospital is short on supplies. He brings Javadi along to have beers with the staff after the shift ends.

Mateo returns in season 2 as part of the night shift staff on July 4.

Donnie Donahue

Donnie Donahue (Brandon Mendez Homer) is a nurse practitioner, and later nurse, working in the ER. In season 2, he is father to a newborn baby, and his experience as a parent helps him care for a baby found abandoned in the ER restroom.

Princess Dela Cruz

Princess Dela Cruz (Kristin Villanueva) is a nurse working in the ER. She is close with Perlah, the two often gossiping with each other in Tagalog.

Jesse Van Horn

Jesse Van Horn (Ned Brower) is a nurse working in the ER. In season 2, Jesse is detained by ICE agents after intervening when they aggressively remove an injured detainee before she can finish receiving treatment. Staff work to track Jesse's whereabouts, but are informed that PTMC's lawyers are busy dealing with the aftermath of the cyberattack on nearby hospitals and will not be able to attend to Jesse's case anytime soon.

Lena Handzo

Lena Handzo (Lesley Boone) is the night-shift charge nurse who also works as a death doula. She assumes the latter role for the family of Roxie Hamler, a woman with advanced lung cancer who arrives at the ER on July 4, and helps Roxie's husband and children come to terms with her impending death.

Dr. Eileen Shamsi

Dr. Eileen Shamsi (Deepti Gupta) is a senior attending surgeon and Victoria Javadi's overbearing mother. She puts pressure on Javadi to pursue surgery over emergency medicine, but Javadi proves her capabilities while treating victims of the Pitt Fest mass shooting, and stands up to her mother's condescension when Shamsi scorns the improvised tactics the doctors are forced to adopt in the absence of resources. Shamsi and Javadi remain distant in season 2, with Shamsi unsuccessfully trying to persuade Robby to allow Javadi to pursue a career outside the ER. Shamsi performs an emergency surgery with her daughter's assistance on patient Austin Green after his abdominal aortic aneurysm ruptures.

Gloria Underwood

Gloria Underwood (Michael Hyatt) is the chief medical officer of the Pitt. She frequently clashes with Robby, who criticizes her for prioritizing bureaucratic concerns such as patient satisfaction scores over quality of care, and urges her to address the hospital's perennial staff shortages. Gloria proves dependable during a mass casualty event following a shooting at Pitt Fest, providing Robby with all the resources he asks for. However, she later admonishes him again upon learning that staff donated their own blood, and that Robby let a potential suspect in the shooting go free earlier in the day despite concerns; Robby finally snaps and loudly berates Gloria in front of the whole staff. At the end of the shift, Gloria commends the Pitt's staff for their heroism in responding to the mass casualty.

Kiara Alfaro

Kiara Alfaro (Krystel V. McNeil) is the department social worker in season 1.

Dr. Yolanda Garcia

Dr. Yolanda Garcia (Alexandra Metz) is a resident surgeon at the Pitt, and is the ER's primary point of contact to the OR. Talented and respected but cocky and often abrasive, Garcia frequently banters with Langdon and subtly flirts with Santos throughout the latter's first shift, though tension briefly arises from Santos accidentally dropping a scalpel on Garcia's foot. In season 2, Garcia and Santos are now having casual sex; Santos wants a more serious relationship, but Garcia does not reciprocate her feelings. Garcia reprimands Santos for her dismissive attitude towards Langdon while treating a patient; Santos later privately confides to Garcia her resentment over being treated like a pariah for reporting Langdon for stealing drugs from the hospital, but Garcia counters that Santos is being ostracized because of her general hostility towards others.

Lupe Perez

Lupe Perez (Tracy Vilar) is the hospital's day-shift ward clerk. During the Pitt Fest shooting, Lupe and social worker Kiara Alfaro set up an area in the hospital for victims' families to identify them based on patient photos. In season 2, Lupe sees several of her fellow Hispanic coworkers fleeing the hospital after ICE agents arrive with an injured detainee.

Dr. John Shen

Dr. John Shen (Ken Kirby) is a night shift senior attending physician. Unlike his more intense counterparts Robby and Abbot, Shen has a casual and laidback demeanor, known for bringing an iced coffee with him to work, and is shown to perform competently under pressure. He and the rest of the night shift assist the day shift in treating victims of the Pitt Fest shooting. In season 2, Shen is the sole attending overseeing the shift the night before July 4, and hands off their patients to Robby. He returns later that night alongside Abbot and oversees several cases, including an asthmatic teenager suffering a pneumothorax, and a pregnant mother suffering pre-eclampsia while attempting a freebirth.

Dr. Emery Walsh

Dr. Emery Walsh (Tedra Millan) is a night shift surgeon, who arrives early to help the day shift treat victims of the Pitt Fest shooting. Like Garcia, she has an abrasive and sarcastic personality, and clashes with Abbot over his improvised tactics to treat victims of the shooting.

Emma Nolan

Emma Nolan (Laëtitia Hollard) is a recent nursing school graduate working in the ER, whom Dana mentors. Despite her initial shyness and anxiety around working in an ER environment, Emma is shown to be a skilled and empathetic nurse, particularly when caring for a homeless patient, Digby, and helping Dana collect a rape kit from a sexual assault victim. At the start of Emma's shift, Dana warns her about the high rates of assault of nurses by patients and informs her of the hospital's code word, "hula hoop", for such emergencies; Emma is indeed assaulted later in her shift when Curtis Larson, a golfer who became belligerent after combining alcohol with cocaine, awakes from sedation in a disoriented state and puts Emma in a chokehold while she is checking his vitals. Dana saves Emma by subduing Larson with Versed; Emma insists on staying to complete her shift, telling Dana she is not a quitter.

Joy Kwon

Joy Kwon (Irene Choi) is a third-year medical student who trains under Whitaker alongside Ogilvie. Joy behaves aloof during the early hours of the July 4 shift, her disinterest often a product of being overshadowed by the arrogant Ogilvie. She later devises a plan for uninsured patient Orlando Diaz to be treated at a far lower cost, and opens up to Mohan about the death of her grandmother and her subsequent discomfort with emergency medicine. When the hospital's computer systems are shut down amid a cyberattack, Joy uses her photographic memory to help staff reconstruct the patient chart on a whiteboard. Joy leaves at the end of her shift despite Langdon admonishing her to stay overtime to help, stressing to him the importance of boundaries given the high rate of burnout amid ER doctors.

James Ogilvie

James Ogilvie (Lucas Iverson) is a well-read but arrogant fourth-year medical student who trains under Whitaker alongside Joy. He has a strained relationship with his father, an English teacher who disapproves of his career in medicine. Ogilvie's pompousness and insensitivity towards patients frequently irk the other staff, including his fellow medical student Joy, who feels overshadowed by him, and McKay, who chastises him for making judgmental comments about an obese patient's weight and later a homeless woman's drug addiction. Ogilvie nearly kills a patient by removing an embedded shard of glass in his body, causing severe bleeding; Robby instructs him never to remove foreign bodies on his own. Ogilvie later bonds with patient Austin Green, who, like Ogilvie's father, is an English teacher; however, Green suffers a rupture of an abdominal aortic aneurysm that Ogilvie and Mohan failed to detect. Ogilvie accompanies Green to surgery, where he ultimately dies. Whitaker finds Ogilvie emotionally devastated in the ambulance bay, and comforts him by telling him about the death of his patient on his own first day. Ogilvie doubts whether he can handle the emergency department and contemplates a move to primary or pediatric care, but Whitaker tells him to go home and rest before making any major career decisions.

Noelle Hastings

Noelle Hastings (Meta Golding) is a nurse and case manager in the ER who is casually dating Robby. She, Mohan, and Joy work together to devise a coverage plan for Orlando Diaz, an uninsured patient, that significantly reduces his out-of-pocket costs. She later bids farewell to Robby for his sabbatical.

Dr. Caleb Jefferson

Dr. Caleb Jefferson (Christopher Thornton) is a psychiatrist. Robby repeatedly blows off Caleb's attempts to speak with him during his last shift before a planned sabbatical, and Caleb unsuccessfully recommends to Robby that he retry therapy. Caleb also diagnoses Jackson Davis, a patient brought in after an outburst at his college library, with possible schizophrenia and manage his symptoms with droperidol. At the end of his shift, Caleb chastises Robby for openly speculating that patient Orlando Diaz attempted suicide, and offers Robby his phone number in case he wants to talk while on his sabbatical.

Dylan Easton

Dylan Easton (Becca Blackwell) is a social worker covering for Kiara on July 4th. He consults with the family of Kylie Connors, a girl with various bodily injuries that Santos suspects are the product of parental abuse, until they learn that she merely has immune thrombocytopenic purpura. Dylan also consults on the case of Jude Augustin, a boy with a fireworks injury who Santos suspects of having consumed alcohol; he learns that Jude's parents were deported to Haiti earlier that year, leaving him largely in the care of his overburdened elder sister, and tells Santos that Jude is better off living in Haiti due to the family's dire financial situation.

Dr. Raymond Javadi

Dr. Raymond Javadi (Usman Ally) is an endocrinologist and Victoria's father.

Trent Norris

Trent Norris (Victor Rivas Rivers) is the chief executive officer of the Pittsburgh Trauma Medical Center. He announces to the staff midway through their July 4th shift that Westbridge Hospital has suffered a cyberattack, and that the Pitt will be preemptively shutting down its computer systems until the crisis is averted.

Monica Peters

Monica Peters (Rusty Schwimmer) is a retired hospital clerk who Dana calls to help manage paperwork during a system shutdown. Though longtime friends with Dana, Monica is gruff and rude to much of the other staff, such as Javadi, and is shown to harbor racist and antiquated attitudes. She eventually leaves about an hour after the hospital systems are restored.

Dr. Crus Henderson

Dr. Crus Henderson (Luke Tennie) is a talented fourth-year resident working on the night shift. He devises a way to diagnose several musculoskeletal injuries using ultrasound alone, eliminating the need for labs and X-rays, and tells Mohan he has applied for the hospital's competitive ultrasound fellowship. Crus also diagnoses a pneumothorax in a boy with asthma, thereby preventing Langdon from performing a fatal chest intubation. Crus and Langdon later treat a man who suffered a spinal dislocation after a car crash; with no neurosurgeon present, Langdon successfully performs an emergency closed reduction of the patient's facet joint despite risk of quadriplegia, earning Crus' praise.

Dr. Nazely Toomarian

Dr. Nazely Toomarian (Sofia Hasmik) is an intern of Armenian descent working on the night shift on July 4th. She and McKay assess a woman with jaundice that Santos later learns was caused by a turmeric overdose. Nazely later helps treat a woman with a STEMI who nearly flatlines, and is mentored by Abbot while helping the night shift treat a pregnant mother suffering from pre-eclampsia attempting a freebirth.

Dr. Brendon Park

Dr. Brendon Park (Lou Ferrigno Jr.) is an intimidating orthopedic surgeon, nicknamed "Park the Shark". He inspects the amputated leg of a woman injured in a waterslide collapse and approves replantation.

Dr. Linda Conley

Dr. Linda Conley (Mary McCormack) is the PTMC's chief neurosurgeon. She tells Javadi that she knew her mother, Dr. Eileen Shamsi, when she was a resident and still pregnant with Javadi. Despite Javadi's initial refusal, Robby volunteers her to assist Conley in placing an external ventricular drain while treating Orlando Diaz, a patient who suffered a traumatic brain injury after a fall.

Dr. Clay Barrett

Dr. Clay Barrett (Geoffrey Owens) is a cardiothoracic surgeon. He assesses CT scan results for Robby's friend Duke Ekins revealing him to have an ascending aortic aneurysm, and tells Robby that Duke can only be brought in for surgery as early as the subsequent week, given that it is a holiday weekend. Robby subsequently slams a water bottle in anger, prompting Dana to take him aside.

Sam Garvin

Sam Garvin (Jona Xiao) is an obstetrics nurse. In the absence of an obstetrician, Sam helps Robby, Abbot, and the night shift crew perform an emergency C-section on a pregnant mother attempting a freebirth.

Theresa Saunders

Theresa Saunders (Joanna Going) is a patient who makes herself sick to come to the ER to report concerns about her son David's behavior.

David Saunders

David Saunders (Jackson Kelly) is Theresa's troubled teenage son, and later, an ER patient.

Louie Cloverfield

Louie Cloverfield (Ernest Harden Jr.) is a patient who frequents the ER and has severe alcoholism.

Doug Driscoll

Doug Driscoll (Drew Powell) is a belligerent patient who has been in the ER waiting room for hours. He clashes with several staff members over having to wait for treatment, despite being reminded that patients are seen based on severity and not order of arrival. Driscoll is initially examined but sent back to the waiting room to await test results. He eventually causes a scene and nearly storms out after having an outburst at Dana and Javadi, but Langdon informs him that he would be leaving against medical advice (AMA) and hands him a form to sign to clear the hospital of liability. Shortly afterwards, Doug punches Dana in the face in the ambulance bay while she is taking a break, and throws the signed AMA form at her. Police later arrest Doug, and staff encourage Dana to press charges. Dana is left deeply traumatized by the assault and nearly quits working at the Pitt because of it.

Minu

Minu (Arun Storrs) is a Nepali woman who was pushed onto the subway train tracks and suffered a severe degloving injury to her foot.

Jereme Spencer

Jereme Spencer (Mackenzie Astin) is the son of an elderly, dying Alzheimer's patient.

Helen Spencer

Helen Spencer (Rebecca Tilney) is Jereme's sister.

Joyce St. Claire

Joyce St. Claire (Ashley Romans) is a woman with sickle cell disease. Paramedics misidentify her as an addict seeking drugs and put her in restraints, but Mohan orders her freed and accurately diagnoses her symptoms, administering drugs to treat her pain and putting her on an antibiotics regime to manage her potential pneumonia. Joyce's wife Ondine arrives to watch over her. Mohan later attributes her intuition regarding Joyce's symptoms to her work studying racial disparities in healthcare, with Joyce, a black woman, more likely to have her symptoms misdiagnosed.

John Bradley

John Bradley (Brandon Keener) is the father of Nick Bradley, a teenager declared braindead after a Xanax overdose. He gets into a confrontation with another patient, Jenna, who was studying with Nick the night he overdosed; she later apologizes. Staff perform an honor walk for Nick, who consented to being an organ donor upon his death, and Robby tells John that the staff would like to attend Nick's funeral; John tearfully accepts.

Lily Bradley

Lily Bradley (Samantha Sloyan) is Nick Bradley's mother. She is devastated upon hearing that her son has been declared braindead from an overdose; Robby orders unnecessary tests to give Nick's parents time to come to terms with his passing. Lily expresses profound gratitude to Robby and the staff for treating Nick and helping she and her husband John through their grief.

Jenna

Jenna (Mika Abdalla) is a college student who overdosed along with Nick Bradley; the two were studying for an exam and took Xanax to fall asleep after having had too much coffee that night. Jenna gets into a verbal confrontation with Nick's father John after he blames her for his son's death, but later apologizes.

Kristi Wheeler

Kristi Wheeler (Abby Ryder Fortson) is a pregnant teenager with an appointment for a medical abortion.

Lynette Wheeler

Lynette Wheeler (Marguerite Moreau) is Kristi's aunt.

Jake Malloy

Jake Malloy (Taj Speights) is the son of Robby's ex-girlfriend Janey Malloy; Robby views him as a son.

Becca King

Becca King (Tal Anderson) is Mel's autistic sister. She lives in an assisted-living facility, with Mel frequently visiting her to make sure she is taken care of; one of their favorite activities is watching the film Elf, which Becca has watched over a hundred times. In season 2, Becca comes to the ER reporting abdominal pain; Langdon examines her and learns she has a urinary tract infection, which Becca admits to Mel is likely a result of having sex with her boyfriend Adam, who Becca met in assisted living and whom Mel was unaware of. Mel is shocked by the news and angrily pressures Becca to divulge more details of the relationship, making Becca cry; Mel later apologizes and learns from Becca that her relationship with Adam is consensual and self-directed, making Mel resent her sister's happiness amidst her own loneliness. While leaving, Becca declines to watch the July 4 fireworks with Mel as they usually do, and instead spends the night at Adam's family's house.

Ginger Kitajima

Ginger Kitajima (Shu Lan Tuan) is an elderly schizophrenic woman who is injured in a fall in her garden.

Piper Fisher

Piper Fisher (Courtney Grosbeck) is a patient brought in for a sexually transmitted infection by a woman named Laura who claims to be her boss. McKay suspects that Piper is a victim of sex trafficking. Piper denies or evades most of McKay's questions asking whether she has been coerced into having sex, but McKay and Dana give her a pen containing a hidden slip of paper with a sex-trafficking hotline. Piper and Laura ultimately leave, but McKay and Dana notice she took the pen they gave her.

Laura Fisher

Laura Fisher (Shani Atias) is Piper's controlling boss, who McKay suspects is trafficking Piper for sex. McKay has the staff distract Laura so she can talk to Piper alone. Laura soon leaves the ER with Piper.

Chad Ashcroft

Chad Ashcroft (Robert Heaps) is McKay's ex and father to their son Harrison. He and McKay have a strained relationship in part due to Chad's irresponsibility as a father, as well as tension between McKay and Chad's new girlfriend, who filed a restraining order against McKay for assaulting her.

Neil McKay

Neil McKay (Brad Dourif) is Cassie's father. Cassie calls him to pick up her son, Harrison, from the hospital as she is busy treating victims of a mass shooting. Neil tells off Cassie's ex, Chad, before leaving with Harrison.

Janey Malloy

Janey Malloy (Sarah Jane Morris) is Robby's ex-girlfriend whose son Jake has a paternal bond with Robby. Janey arrives at the hospital after hearing that Jake attended Pitt Fest, where a mass shooting took place, and comforts him amid the death of his girlfriend Leah in the shooting.

Troy Digby

Troy Digby (Charles Baker) is a homeless man who comes to the ER seeking to remove a cast from his arm. After other patients in the waiting room complain about his foul odor, Digby is admitted as a patient and given a shower by Dana and Emma. Mohan subsequently cuts open Digby's arm cast to reveal maggots living underneath, his wound having become infected. Staff treat his infection, and Dana and Emma later give Digby a shave and a haircut, leaving him emotional both with gratitude for the nurses and distress that his family will not recognize him. Digby reveals that he has an adult daughter who lives in his former home; Emma, who learns that Digby danced with his daughter at her wedding, assures him that his daughter will always remember him.

Harlow Graham

Harlow Graham (Jessica "Limer" Flores) is a deaf patient suffering from neck pain. After Harlow's interpreter is called away on an emergency, hospital staff struggle to communicate with her while awaiting a new interpreter; a VRI is used until a system shutdown renders it non-functional, and Santos unsuccessfully tries to use a pen and paper as an alternative. A new in-person interpreter eventually arrives; Santos learns that Harlow's neck pain comes from poor posture while working on her laptop, and administers a local anesthetic. Santos later expresses guilt for the amount of time it took to treat Harlow for what was ultimately a simple diagnosis.

Evelyn Bostick

Evelyn Bostick (Jayne Taini) is a patient with Alzheimer's whose husband Ethan dies in the hospital shortly before she too is brought in as a patient. Due to her Alzheimer's, Whitaker and Ogilvie are forced to inform Evelyn multiple times that her husband has died.

Kylie Conners

Kylie Conners (Annabelle Toomey) is a 9-year-old patient brought into the ER by her father's girlfriend after suffering a chin injury from falling down the stairs. Santos notices bruises across Kylie's body and collects a urine sample from her containing hematuria, and suspects that her father is abusing her. Kylie's father, Benny, is brought in for questioning and becomes irate upon being accused of abuse; Dana breaks up the confrontation by announcing that Kylie was found to have a low platelet count, indicating immune thrombocytopenic purpura that explains her bruising. Santos tells Kylie that her treatment will require her to stay in the hospital for several days. Benny and his girlfriend subsequently have an argument and break up.

Orlando Diaz

Orlando Diaz (William Guirola) is a working-class construction worker who arrives at the emergency department unconscious after a fall and is diagnosed with severe diabetic ketoacidosis, which Mohan learns was caused by Orlando rationing insulin after losing his health insurance. Mohan and the team stabilize him while learning he cannot afford proper diabetes management, placing financial strain on him and his family. Mohan, Joy, and case manager Noelle Hastings devise a treatment plan that drastically lowers Orlando's out-of-pocket costs, but Orlando grows increasingly distressed about his mounting medical debt, and refuses to let his daughter start a GoFundMe for financial assistance. He later attempts to leave against medical advice to avoid further expenses; Mohan briefly persuades him to stay and prepares supplies for at-home care, but Orlando ultimately leaves before completing treatment, prompting Mohan and Abbot to arrange delivery of essential medical supplies to his home via Uber.

Orlando is later brought back to the ER hours later after having suffered a worse fall, resulting in a basilar skull fracture and possible severe brain damage, and is sent to neurosurgery. Mohan is devastated by Orlando's condition and feels responsible for not doing enough to convince him to stay, but Robby tells her not to blame herself, suggesting that Orlando attempted suicide due to his high medical debt.

Jackson Davis

Jackson Davis (Zack Morris) is a patient brought to the ER in a psychotic state after having an outburst at his college library while studying for the bar exam. Jackson was illegally tased in the neck by security guard Tony Chinchiolo; Mel and Robby remove the taser barbs. Jackson's symptoms are treated with droperidol by psychiatrist Caleb Jefferson, and his sister Jada arrives, distressed over his condition and shocked to learn of his outburst. Upon awakening, Jackson tells Caleb of voices he was hearing. Jackson's parents later arrive; the family is informed that Jackson may be suffering from schizophrenia. Javadi introduces Jackson's family to Nicole Steadman, a parent-support advocate, who helps them come to terms with their son's mental-health issues; Jackson's father eventually admits that the death of his brother (Jackson's uncle) was a suicide, suggesting a family history of mental illness.

Yana Kovalenko

Yana Kovalenko (Irina Dubova) is a patient brought in on July 4 after burning her hand upon dropping a samovar. Yana bonds with Robby over their shared Jewish faith, while chiding him over his plan to take a three-month sabbatical riding a motorcycle. Robby learns that Yana attends the Tree of Life synagogue and survived the shooting there in 2018, and realizes that Yana dropped the samovar due to her PTSD being triggered by the sound of fireworks. Yana later thanks her nurse Perlah, a Muslim, for the support shown by the Pittsburgh Muslim community to victims of the shooting.

Brian Hancock

Brian Hancock (Lawrence Robinson) is a patient with a soccer injury who asks McKay out on a date, which she accepts. She invites him along to an art gallery exhibition she plans to attend, but after having to stay overtime amid a system shutdown, McKay suggests she may cancel the date and relax by herself at home.

Roxie Hamler

Roxie Hamler (Brittany Allen) is a patient with advanced lung cancer.

Paul Hamler

Paul Hamler (Taylor Handley) is Roxie's husband.

Lloyd Wilkins

Lloyd Wilkins (John Getz) is Roxie's father.

Cora Wilkins

Cora Wilkins (Bonita Friedericy) is Roxie's mother.

Ilana Miller

Ilana Miller (Tina Ivlev) is a sexual assault victim. Dana and Emma gently examine her and collect her DNA samples for rape kit. At one point, Ilana panics and hesitates to press charges against her assailant, as he was a friend of hers, but ultimately chooses to complete her examination. Dana is emotionally moved by the experience, especially after Ilana thanks her for being there on a traumatic day. Dana is later enraged to find another rape kit in storage that the police failed to collect for two weeks.

Austin Green

Austin Green (Johnny Sneed) an English professor at Point Park University who presents to the ER with left flank pain consistent with a recurrent kidney stone. Ogilvie and Mohan examine him and administer ketorolac for his pain; Ogilvie, whose father is also an English teacher, bonds with Green and gives him a copy of James Baldwin's Notes of a Native Son to read while awaiting discharge. However, Green later suffers a ruptured abdominal aortic aneurysm that Ogilvie and Mohan failed to detect; despite emergency surgery performed by Javadi and Dr. Shamsi, Green dies in the operating room, leaving Ogilvie devastated. The hospital's computer systems, which had gone offline during a cyberattack, reveal that Green's AAA was diagnosed over a year ago.

Derek Foster

Derek Foster (David Fumero) is the victim of a waterslide collapse that leaves him with a pneumothorax as well as a degloving injury on his ring finger. Langdon and Santos clash while treating him, with Santos dismissing Langdon's guidance over her grudge against him. Foster, however, is mostly concerned with finding his son, who was also at the water park where the slide collapsed.

Duke Ekins

Duke Ekins (Jeff Kober) is a motorcycle engineer and old friend of Robby. After Duke complains about hoarseness in his throat, Robby has him come in for a check-up on his last shift before a sabbatical he plans to spend riding his motorcycle cross-country. Duke's X-ray detects an enlarged mediastinum; Robby delays leaving for trip until CT scan results arrive. Duke notices Robby behaving erratically and infers that he feels a compulsion to stay in the ER despite the toll it takes on him and his desire to escape.

The CT scan reveals that Duke has an ascending aortic aneurysm that will require surgery and months of aftercare, with a 50% chance of death otherwise. Duke helps fix Robby's motorcycle after an ambulance accidentally knocks it over, and has an honest conversation with him afterwards, where Robby finally admits that he is suicidal and that his sabbatical is an attempt to escape his anguish. Duke asks Robby whether running away is the legacy he wants to leave for his students. He and Robby shake hands before he departs, with Duke making Robby promise to return from his trip.

Brenda Azurmendi

Brenda Azurmendi (Cathryn Dylan Ortiz) is a woman who brings her son Micah into the ER after he suffers heat stroke from falling asleep inside his mother's unlocked car on July 4. Joy blames Brenda for leaving her son unattended and speculates whether Brenda intentionally put him in harm's way. Feeling guilty after learning that Micah may be cognitively impaired as a result of the heat stroke, Brenda attempts suicide by stepping into oncoming traffic, but Al-Hashimi stops her and has her put on an involuntary psychiatric hold. Robby is unsettled while watching Al-Hashimi question Brenda about whether she has previously experienced suicidal thoughts, as he himself is suicidal.

Curtis Larson

Curtis Larson (Travis Van Winkle) is a patient brought in after drunkenly attacking his friends while golfing and subsequently having to be sedated by paramedics. While Emma checks his vitals, Larson awakens in a disoriented state and puts her in a chokehold, but Dana subdues him with a shot of Versed she had in her pocket; he is also left with a bloody nose that Dana refuses to explain to Robby. Labs reveal that Larson combined alcohol with cocaine, producing cocaethylene that sent him into a psychotic state. McKay offers him resources for rehab, but he harshly rebukes her, and is further incensed to learn that police will be questioning him for his assault.

Robby criticizes Dana's handling of Larson, warning that her use of force and unauthorized use of a controlled substance could jeopardize her nursing license; he also intuits that Dana had been carrying Versed as a defense mechanism after being assaulted by patient Doug Driscoll. Dana nevertheless defends her actions.

Eddie Cohen

Eddie Cohen (Dann Florek) is the husband of patient Frida Cohen, whom he accidentally hit with their car and who suffered a hairline fracture in her hip as a result. Mohan has Eddie inspected as well, learning he struggles to maintain balance, and learns that his disorientation was caused by a combination of his various medicines prescribed by different doctors. Mohan recommends moving the Cohens to a care home, but learns that their daughter Carrie has been unsuccessfully trying to convince her parents of the same. Mohan and Mel eventually devise a plan for the Cohens to receive at-home care, leaving Eddie grateful to them for listening.

Judith Lastrade

Judith Lastrade (Nicole Wolf) is a pregnant mother attempting a freebirth, who arrives at the ER after reporting headaches. Staff learn she has pre-eclampsia; Nicole soon suffers a seizure, forcing Abbot and the night shift crew to sedate her and fit her with an EEG to monitor her vitals despite her initial refusal of medical care. Robby and Abbot are eventually forced to perform an emergency C-section to save both Judith and her newborn daughter, who emerges from the womb appearing blue, but soon recovers. Abbot uses Judith's case as an example of the importance of the work Robby performs while talking him out of his suicidal urge and fatigue from the ER.