List of UK Independent Singles Chart number ones of 2021

Chart date (week ending)	Song	Artist(s)	Record label	References
7 January	"Merry Xmas Everybody"	Slade	BMG	^[1]
14 January	"Really Love"	KSI featuring Craig David and Digital Farm Animals		^[2]
21 January				^[3]
28 January				^[4]
4 February				^[5]
11 February				^[6]
18 February				^[7]
25 February	"Commitment Issues"	Central Cee	Central Cee	^[8]
4 March				^[9]
11 March				^[10]
18 March				^[11]
25 March				^[12]
1 April				^[13]
8 April				^[14]
15 April				^[15]
22 April				^[16]
29 April				^[17]
6 May	"Didn't Know"	Tom Zanetti	Sic	^[18]
13 May				^[19]
20 May				^[20]
27 May				^[21]
3 June	"Butter"	BTS	Big Hit Entertainment	^[22]
10 June				^[23]
17 June				^[24]
24 June	"Didn't Know"	Tom Zanetti	Sic	^[25]
1 July	"Holiday"	KSI	BMG	^[26]
8 July				^[27]
15 July				^[28]
22 July				^[29]
29 July ^[b]				^[30]
5 August				^[31]
12 August				^[32]
19 August				^[33]
26 August				^[34]
2 September				^[35]
9 September				^[36]
16 September				^[37]
23 September	"Obsessed with You"	Central Cee	Central Cee	^[38]
30 September	"Love Nwantiti (Ah Ah Ah)"	CKay	WM South Africa	^[39]
7 October				^[40]
14 October				^[41]
21 October				^[42]
28 October				^[43]
4 November				^[44]
11 November	"Monster Mash"	Bobby Boris Pickett	The Monster Mash.Com	^[45]
18 November	"Love Tonight"	Shouse	Hell Beach	^[46]
25 November	"Someone like You"	Adele	XL	^[47]
2 December	"Someone like You"	Adele	XL	^[48]
9 December	"Merry Xmas Everybody"	Slade	BMG	^[49]
16 December				^[50]
23 December				^[51]
30 December ^[a]	"Sausage Rolls for Everyone"	LadBaby featuring Ed Sheeran and Elton John	FrtyFve	^[52]

Chart history