Lomedeucitinib

Lomedeucitinib
Clinical data
Other names	BMS-986322
Identifiers
	IUPAC name 4-{[3-(methylsulfonyl)pyridin-2-yl]amino}-6-[((2R)-spiro[2.2]pentane-2-carbonyl)amino]-N-(trideuteriomethyl)pyridazine-3-carboxamide;
CAS Number	2328068-29-5;
PubChem CID	138620496;
IUPHAR/BPS	13210;
ChemSpider	129427731;
UNII	EYQ7KA55XA;
KEGG	D12725;
ChEMBL	ChEMBL5314608;
Chemical and physical data
Formula	C18H17D3N6O4S
Molar mass	419.47 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)[C@@H]2CC23CC3)cc1Nc1ncccc1S(C)(=O)=O;
	InChI InChI=1S/C18H20N6O4S/c1-19-17(26)14-11(21-15-12(29(2,27)28)4-3-7-20-15)8-13(23-24-14)22-16(25)10-9-18(10)5-6-18/h3-4,7-8,10H,5-6,9H2,1-2H3,(H,19,26)(H2,20,21,22,23,25)/t10-/m0/s1/i1D3; Key:VWIVBQZLVAGLMH-ASGODXDTSA-N;

Other namesBMS-986322

Lomedeucitinib is an investigational new drug that is being evaluated for the treatment of psoriasis and psoriatic arthritis. It is a tyrosine kinase 2 (TYK2) inhibitor.^[1]

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