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Lu AE04621

Pharmaceutical compound From Wikipedia, the free encyclopedia

Lu AE04621 is a dopamine receptor agonist which is or was under development for the treatment of Parkinson's disease but has not been marketed.[1][2][3] It is taken orally.[1] The drug is said to be a prodrug of the catecholamine Lu AA40326 and to act as a dual dopamine D1 and D2 receptor agonist.[1][2][3][4] Lu AE04621 is or was under development by Lundbeck.[1][2] As of November 2023, it is in phase 1 clinical trials and has been since at least 2016, but no recent development has been reported since February 2019.[1] The chemical structure of Lu AE04621 has not yet been disclosed.[1][2][3] However, it may be a prodrug of 5,6-diOH-DPAT or a related approach.[2]

Other namesLu-AE04621; Lu AE 04621; LuAE04621
ATC code
  • None
Quick facts Clinical data, Other names ...
Lu AE04621
Clinical data
Other namesLu-AE04621; Lu AE 04621; LuAE04621
Routes of
administration
Oral[1]
Drug classDopamine receptor agonist; Dopamine D1 and D2 receptor agonist
ATC code
  • None
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