Luteolin-7-O-glucuronide
Chemical compound
From Wikipedia, the free encyclopedia
Luteolin-7-O-glucuronide is a chemical compound that is classified as a flavone.
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| IUPAC name
(2S,3S,4S,5R)-6-[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate | |
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| Identifiers | |
3D model (JSmol) |
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PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
| C21H18O12 | |
| Molar mass | 462.363 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It is found in Acanthus hirsutus[1] and in rye (Secale cereale).[2][3]
Biosynthesis and metabolism
Luteolin 7-O-glucuronosyltransferase is the glucuronosyltransferase that uses UDP-glucuronate to convert luteolin its glucuronide by adding a sugar acid at one of the phenolic hydroxy groups, with uridine diphosphate (UDP) as byproduct:[2]
Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase is an enzyme that adds a second sugar group to luteolin-7-O-glucuronide to give luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide).[2][3]
luteolin-7-O-glucuronide + UDP-glucuronate
-β-D-glucuronide).svg)
luteolin 7-O-(β-D-glucuronosyl-(1→2)-β-D-glucuronide)
