MARCH2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
E3 ubiquitin-protein ligase MARCH2 is an enzyme that in humans is encoded by the MARCH2 gene.[5][6][7] It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins.[8] MARCH2 has been shown to negatively regulate NF-κB essential modulator function upon viral and bacterial infections.[9]
| MARCHF2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | MARCHF2, MARCH-II, RNF172, HSPC240, membrane associated ring-CH-type finger 2, MARCH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 613332; MGI: 1925915; HomoloGene: 9539; GeneCards: MARCHF2; OMA:MARCHF2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene name error in Excel
Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH2 gene in Microsoft Excel.[10] This is due to Excel's autocorrect feature treating the MARCH gene as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.[11] The issue can be prevented by using an alias name such as MARCHF2, prepending with an apostrophe ('), or preformatting the cell as text.
