MBOAT7

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Lysophospholipid acyltransferase 7 also known as membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is an enzyme that in humans is encoded by the MBOAT7 gene.[5] It is homologous to other membrane-bound O-acyltransferases.[6][7]

AliasesMBOAT7, BB1, LENG4, LPIAT, LRC4, MBOA7, OACT7, hMBOA-7, membrane bound O-acyltransferase domain containing 7, MRT57, LPLAT
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MBOAT7
Identifiers
AliasesMBOAT7, BB1, LENG4, LPIAT, LRC4, MBOA7, OACT7, hMBOA-7, membrane bound O-acyltransferase domain containing 7, MRT57, LPLAT
External IDsOMIM: 606048; MGI: 1924832; HomoloGene: 11510; GeneCards: MBOAT7; OMA:MBOAT7 - orthologs
EC number2.3.1.n4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001146056
NM_001146082
NM_001146083
NM_024298

NM_029934

RefSeq (protein)

NP_001139528
NP_001139554
NP_001139555
NP_077274

NP_084210

Location (UCSC)Chr 19: 54.17 – 54.19 MbChr 7: 3.68 – 3.7 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the membrane-bound O-acyltransferase family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the re-acylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle.[5][6]

References

Further reading

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