MBOAT7

MBOAT7
Identifiers
Aliases	MBOAT7, BB1, LENG4, LPIAT, LRC4, MBOA7, OACT7, hMBOA-7, membrane bound O-acyltransferase domain containing 7, MRT57, LPLAT
External IDs	OMIM: 606048; MGI: 1924832; HomoloGene: 11510; GeneCards: MBOAT7; OMA:MBOAT7 - orthologs
EC number	2.3.1.n4
Gene location (Human)
Chr.	Chromosome 19 (human)
End	54,189,882 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	3,696,522 bp
RNA expression pattern
	Top expressed in
	blood; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; superior frontal gyrus; ; stromal cell of endometrium; ; right frontal lobe; ; prefrontal cortex; ; hypothalamus;
	Top expressed in
	granulocyte; ; ventromedial nucleus; ; dorsomedial hypothalamic nucleus; ; central gray substance of midbrain; ; superior frontal gyrus; ; primary visual cortex; ; nucleus of stria terminalis; ; paraventricular nucleus of hypothalamus; ; lateral hypothalamus; ; arcuate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; protein binding; 2-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity; lysophospholipid acyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; mitochondria associated membranes; endoplasmic reticulum;
Biological process	phosphatidylinositol acyl-chain remodeling; phosphatidylinositol metabolic process; ventricular system development; lipid metabolism; phospholipid biosynthetic process; phospholipid metabolic process; layer formation in cerebral cortex;
	Sources:Amigo / QuickGO
Orthologs
	79143
	77582
ENSG00000273592; ENSG00000278519; ENSG00000274194; ENSG00000125505; ENSG00000277025;
	ENSG00000275118; ENSG00000276935; ENSG00000277733; ENSG00000277923; ENSG00000278322
	ENSMUSG00000035596
	Q96N66
	Q8CHK3
	NM_001146056; NM_001146082; NM_001146083; NM_024298
	NM_029934
	NP_001139528; NP_001139554; NP_001139555; NP_077274
	NP_084210
	Wikidata
View/Edit Human	View/Edit Mouse

AliasesMBOAT7, BB1, LENG4, LPIAT, LRC4, MBOA7, OACT7, hMBOA-7, membrane bound O-acyltransferase domain containing 7, MRT57, LPLAT

External IDsOMIM: 606048; MGI: 1924832; HomoloGene: 11510; GeneCards: MBOAT7; OMA:MBOAT7 - orthologs

EC number2.3.1.n4

Chr.Chromosome 19 (human)^[1]

Lysophospholipid acyltransferase 7 also known as membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is an enzyme that in humans is encoded by the MBOAT7 gene.^[5] It is homologous to other membrane-bound O-acyltransferases.^[6]^[7]

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[2]

[3]

[4]

[5]

[6]

[7]

MBOAT7

References

Further reading

Related Articles

Related Articles

"The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification"

"Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol"

"Recent progress on acyl CoA: lysophospholipid acyltransferase research"

"Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils"