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MDFEM

Pharmaceutical compound From Wikipedia, the free encyclopedia

MDFEM, also known as 4-(2,2-difluoroethoxy)-2,5-dimethoxyamphetamine, is a serotonin receptor modulator of the phenethylamine, amphetamine, and DOx families.[1][2][3] It is a derivative of the DOx psychedelics TMA-2 and MEM in which the 4-position substituent has been extended.[1][2][3] The properties and effects of MDFEM in humans appear to be unknown.[1][2][3] The drug is a partial agonist of the serotonin 5-HT2A and 5-HT2B receptors and also shows other receptor interactions.[3] MDFEM was first described in the scientific literature by Daniel Trachsel by 2012.[1][2][3]

Other names4-(2,2-Difluoroethoxy)-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-4-(2,2-difluoroethoxy)amphetamine
ATC code
  • None
FormulaC13H19F2NO3
Quick facts Clinical data, Other names ...
MDFEM
Clinical data
Other names4-(2,2-Difluoroethoxy)-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-4-(2,2-difluoroethoxy)amphetamine
Drug classSerotonin receptor modulator; Serotonin 5-HT2A receptor agonist
ATC code
  • None
Identifiers
  • 1-[4-(2,2-difluoroethoxy)-2,5-dimethoxyphenyl]propan-2-amine
Chemical and physical data
FormulaC13H19F2NO3
Molar mass275.296 g·mol−1
3D model (JSmol)
  • CC(N)CC1=CC(OC)=C(OCC(F)F)C=C1OC
  • InChI=1S/C13H19F2NO3/c1-8(16)4-9-5-11(18-3)12(6-10(9)17-2)19-7-13(14)15/h5-6,8,13H,4,7,16H2,1-3H3
  • Key:AXKORAKXKXDBAF-UHFFFAOYSA-N
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