MED19

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Mediator complex subunit 19 (Med19) is a protein that in humans is encoded by the MED19 gene. [5]

AliasesMED19, DT2P1G7, LCMR1, MED19AS, mediator complex subunit 19
End57,712,221 bp[1]
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MED19
Identifiers
AliasesMED19, DT2P1G7, LCMR1, MED19AS, mediator complex subunit 19
External IDsOMIM: 612385; MGI: 1914234; HomoloGene: 14684; GeneCards: MED19; OMA:MED19 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_153450
NM_001317078

NM_025885

RefSeq (protein)

NP_001304007
NP_703151

NP_080161

Location (UCSC)Chr 11: 57.7 – 57.71 MbChr 2: 84.51 – 84.52 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a subunit of the Mediator complex, which binds to gene-specific regulatory factors and provides support for the basal RNA polymerase II transcription machinery. This gene has been implicated in the growth of several types of cancer, and inhibition of its expression inhibits the growth and spread of these cancers. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].

See also

References

Further reading

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