MEOX2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Mesenchyme homeobox 2 (MEOX2) is a protein that in humans is encoded by the MEOX2 gene.[5][6]
Function
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing transcription factor genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.[6] MEOX2 has been implicated in the initiation of tumors in glioma.[7] Additionally, MEOX2 influences several critical processes in lung cancer, including cellular proliferation, invasion, metastasis, angiogenesis, and the development of drug resistance.[8][9][10]
