MES207

MES207
Identifiers
	IUPAC name 4-anilino-1-benzyl-N-[2-(diaminomethylideneamino)ethyl]piperidine-4-carboxamide;
PubChem CID	101882819;
IUPHAR/BPS	11235;
ChemSpider	58129784;
ChEMBL	ChEMBL3361425;
Chemical and physical data
Formula	C22H30N6O
Molar mass	394.523 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CN(CCC1(C(=O)NCCN=C(N)N)NC2=CC=CC=C2)CC3=CC=CC=C3;
	InChI InChI=1S/C22H30N6O/c23-21(24)26-14-13-25-20(29)22(27-19-9-5-2-6-10-19)11-15-28(16-12-22)17-18-7-3-1-4-8-18/h1-10,27H,11-17H2,(H,25,29)(H4,23,24,26); Key:SCPYAGLHLAAYFP-UHFFFAOYSA-N;

MES207 is a drug used in scientific research which acts as a potent and selective antagonist for the neuropeptide FF receptor NPFF1, with 17x selectivity over the closely related receptor NPFF2. It prevented opioid-induced hyperalgesia in animal models.^[1]^[2]

PubChem CID

101882819

IUPHAR/BPS

11235

ChemSpider

58129784

ChEMBL

ChEMBL3361425

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[2]

MES207

References

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Identifiers

IUPAC name 4-anilino-1-benzyl-N-[2-(diaminomethylideneamino)ethyl]piperidine-4-carboxamide
PubChem CID	101882819
IUPHAR/BPS	11235
ChemSpider	58129784
ChEMBL	ChEMBL3361425
Chemical and physical data
Formula	C₂₂H₃₀N₆O
Molar mass	394.523 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CN(CCC1(C(=O)NCCN=C(N)N)NC2=CC=CC=C2)CC3=CC=CC=C3
InChI InChI=1S/C22H30N6O/c23-21(24)26-14-13-25-20(29)22(27-19-9-5-2-6-10-19)11-15-28(16-12-22)17-18-7-3-1-4-8-18/h1-10,27H,11-17H2,(H,25,29)(H4,23,24,26) Key:SCPYAGLHLAAYFP-UHFFFAOYSA-N