MGAT5B

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B is an enzyme that in humans is encoded by the MGAT5B gene.^[5][6][7]

AliasesMGAT5B, GnT-IX, GnT-VB, mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B, alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

External IDsOMIM: 612441; MGI: 3606200; GeneCards: MGAT5B

Chr.Chromosome 17 (human)^[1]

End76,950,393 bp^[1]

Quick facts Identifiers, Aliases ...

MGAT5B
Identifiers
Aliases	MGAT5B, GnT-IX, GnT-VB, mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B, alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
External IDs	OMIM: 612441; MGI: 3606200; GeneCards: MGAT5B
Enzyme activity EC # BRENDA ExPASy KEGG MetaCyc 2.4.1.155 ↗ ↗ ↗ ↗
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.2 Start 76,868,404 bp[1] End 76,950,393 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 E2 Start 116,809,689 bp[2] End 116,877,774 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right frontal lobe Brodmann area 9 oocyte cingulate gyrus anterior cingulate cortex putamen prefrontal cortex caudate nucleus nucleus accumbens amygdala Top expressed in dentate gyrus of hippocampal formation granule cell superior frontal gyrus primary visual cortex lumbar subsegment of spinal cord ventricular zone ganglionic eminence medial dorsal nucleus superior colliculus piriform cortex lateral geniculate nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity protein binding metal ion binding glycosyltransferase activity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity manganese ion binding Cellular component integral component of membrane Golgi membrane membrane Golgi apparatus Biological process protein glycosylation protein N-linked glycosylation protein O-linked glycosylation via serine Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 146664 268510 Ensembl ENSG00000167889 ENSMUSG00000043857 UniProt Q3V5L5 Q765H6 RefSeq (mRNA) NM_001199172 NM_144677 NM_198955 NM_172948 RefSeq (protein) NP_001186101 NP_653278 NP_945193 NP_766536 Location (UCSC) Chr 17: 76.87 – 76.95 Mb Chr 11: 116.81 – 116.88 Mb PubMed search [3] [4]
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