MLLT1

MLLT1
Identifiers
Aliases	MLLT1, ENL, LTG19, YEATS1, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1, super elongation complex subunit, MLLT1 super elongation complex subunit
External IDs	OMIM: 159556; MGI: 1927238; HomoloGene: 4339; GeneCards: MLLT1; OMA:MLLT1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	6,279,975 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	57,242,415 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; placenta; ; right uterine tube; ; right hemisphere of cerebellum; ; myocardium of left ventricle; ; tibialis anterior muscle; ; nucleus accumbens; ; right frontal lobe; ; ventricular zone; ; decidua;
	Top expressed in
	ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; genital tubercle; ; lip; ; superior frontal gyrus; ; primary visual cortex; ; neural tube; ; tail of embryo; ; perirhinal cortex; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription elongation factor complex; nucleus; fibrillar center; nucleoplasm; cytosol;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; negative regulation of protein kinase activity; transcription, DNA-templated; transcription elongation from RNA polymerase II promoter; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4298
	64144
	ENSG00000130382
	ENSMUSG00000024212
	Q03111
	Q9ERL0
	NM_005934
	NM_022328
	NP_005925
	NP_071723
	Wikidata
View/Edit Human	View/Edit Mouse

Protein ENL is a protein that in humans is encoded by the MLLT1 gene.^[5]

AliasesMLLT1, ENL, LTG19, YEATS1, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1, super elongation complex subunit, MLLT1 super elongation complex subunit

External IDsOMIM: 159556; MGI: 1927238; HomoloGene: 4339; GeneCards: MLLT1; OMA:MLLT1 - orthologs

Chr.Chromosome 19 (human)^[1]

End6,279,975 bp^[1]

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[5]

[1]

[2]

[3]

[4]

MLLT1

Interactions

References

Further reading

External links

Related Articles

Related Articles

"Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia"

"Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice"

"Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner"

"Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited"