MLX (gene)
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Max-like protein X is a protein that in humans is encoded by the MLX gene.[5][6]
External IDsOMIM: 602976; MGI: 108398; HomoloGene: 7969; GeneCards: MLX; OMA:MLX - orthologs
Function
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[6]