MTDA

Pharmaceutical compound From Wikipedia, the free encyclopedia

MTDA, or MPDA, also known as 3-methoxy-4,5-trimethylenedioxyamphetamine or as 5-methoxy-TDA, is a chemical compound of the phenethylamine and amphetamine families related to the MDxx compounds like MDMA and the EDxx compounds like EDMA.[1][2][3] It is the 5-methoxy derivative of 3,4-trimethylenedioxyamphetamine (TDA) and the analogue of MMDA (5-methoxy-MDA) and MEDA (5-methoxy-EDA) in which the 3,4-alkylenedioxy ring is a further-expanded 3,4-trimethylenedioxy ring.[1][2][3] It was synthesized, tested, and described by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1][2][3] He tested it at doses of up to 8 mg orally and observed no activity.[1][2][3] He did not expect any activity and did not test higher doses before abandoning it, due to it being "not an interesting compound".[1][2][3] MTDA was first described in the scientific literature by Shulgin by 1964.[4][5]

Other namesMPDA; 3-Methoxy-4,5-trimethylenedioxyamphetamine; 5-Methoxy-3,4-trimethylenedioxyamphetamine; 5-Methoxy-TDA; 5-MeO-TDA
ATC code
  • None
FormulaC13H19NO3
Quick facts Clinical data, Other names ...
MTDA
Clinical data
Other namesMPDA; 3-Methoxy-4,5-trimethylenedioxyamphetamine; 5-Methoxy-3,4-trimethylenedioxyamphetamine; 5-Methoxy-TDA; 5-MeO-TDA
ATC code
  • None
Identifiers
  • 1-(6-methoxy-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)propan-2-amine
PubChem CID
Chemical and physical data
FormulaC13H19NO3
Molar mass237.299 g·mol−1
3D model (JSmol)
  • CC(CC1=CC2=C(C(=C1)OC)OCCCO2)N
  • InChI=1S/C13H19NO3/c1-9(14)6-10-7-11(15-2)13-12(8-10)16-4-3-5-17-13/h7-9H,3-6,14H2,1-2H3
  • Key:XCXNZPQOBJFUIH-UHFFFAOYSA-N
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