MUBII-TB-DB
From Wikipedia, the free encyclopedia
capturedTuberculosis antibiotic resistance genes
| Content | |
|---|---|
| Description | A database that documents and tracks tuberculosis antibiotic resistance genes. |
| Data types captured | Tuberculosis antibiotic resistance genes |
| Organisms | Bacteria |
| Contact | |
| Primary citation | PMID 24731071 |
| Access | |
| Website | umr5558-bibiserv |
| Miscellaneous | |
| Bookmarkable entities | yes |
MUBII-TB-DB is a database that focuses on tuberculosis antibiotic resistance genes.[1] It is a highly structured, text-based database focusing on Mycobacterium tuberculosis at seven different mutation loci: rpoB, pncA, katG; mabA(fabG1)-inhA, gyrA, gyrB, and rrs.[1][2][3][4][5] MUBII analyzes the query using two parallel strategies: 1). A BLAST search against previously mutated sequences. 2). Alignment of query sequences with wild-type sequences. MUBII outputs graphs of alignments and description of the mutation and therapeutic significance.[1] Therapeutically relevant mutations are tagged as "High-Confident" based on the criteria set by Sandgren et al.[6] MUBII-TB-DB provides a platform that is easy to use for even users that are not trained in bioinformatics.[1]
