MYLK3

MYLK3
Identifiers
Aliases	MYLK3, MLCK, MLCK2, caMLCK, myosin light chain kinase 3
External IDs	OMIM: 612147; MGI: 2443063; GeneCards: MYLK3
Enzyme activity
Gene location (Human)
Chr.	Chromosome 16 (human)
End	46,790,407 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	86,112,974 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; right ventricle; ; myocardium of left ventricle; ; right auricle of heart; ; Skeletal muscle tissue of biceps brachii; ; body of tongue; ; apex of heart; ; thoracic diaphragm; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle;
	Top expressed in
	myocardium of ventricle; ; atrium; ; interventricular septum; ; atrioventricular valve; ; epithelium of small intestine; ; esophagus; ; migratory enteric neural crest cell; ; endocardial cushion; ; left ventricle; ; bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	calmodulin-dependent protein kinase activity; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; ATP binding; myosin light chain kinase activity;
Cellular component	cytoplasm; actin cytoskeleton; cytosol; intracellular anatomical structure;
Biological process	protein phosphorylation; positive regulation of sarcomere organization; regulation of vascular permeability involved in acute inflammatory response; sarcomere organization; cellular response to interleukin-1; phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; intracellular signal transduction; sarcomerogenesis; cardiac myofibril assembly;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	91807
	213435
	ENSG00000140795
	ENSMUSG00000031698
	Q32MK0
	Q3UIZ8
	NM_001308301; NM_182493
	NM_001297612; NM_175441
	NP_001295230; NP_872299
	NP_001284541; NP_780650
	Wikidata
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