Macrophage-capping protein

CAPG
Identifiers
Aliases	CAPG, AFCP, HEL-S-66, MCP, capping actin protein, gelsolin like
External IDs	OMIM: 153615; MGI: 1098259; GeneCards: CAPG
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1J72, 1JHW
Gene location (Human)
Chr.	Chromosome 2 (human)
End	85,418,432 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	72,539,966 bp
RNA expression pattern
	Top expressed in
	monocyte; ; skin of abdomen; ; left lobe of thyroid gland; ; granulocyte; ; right lobe of thyroid gland; ; skin of leg; ; upper lobe of left lung; ; right lung; ; ectocervix; ; gums;
	Top expressed in
	granulocyte; ; corneal stroma; ; lip; ; decidua; ; ankle joint; ; conjunctival fornix; ; esophagus; ; stroma of bone marrow; ; gastrula; ; ankle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-containing complex binding; actin binding; protein binding; protein domain specific binding; cadherin binding; actin filament binding;
Cellular component	cytoplasm; F-actin capping protein complex; melanosome; centriole; mitotic spindle; nucleolus; extracellular exosome; nucleus; Flemming body; nucleoplasm; extracellular region; ruffle; lamellipodium; cell projection;
Biological process	barbed-end actin filament capping; extracellular matrix disassembly; positive regulation of podosome assembly; actin filament capping; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	822
	12332
	ENSG00000042493
	ENSMUSG00000056737
	P40121
	P24452
NM_001256139; NM_001256140; NM_001747; NM_001320732; NM_001320733;
	NM_001320734
	NM_001042534; NM_001271395; NM_001271415; NM_007599
NP_001243068; NP_001243069; NP_001307661; NP_001307662; NP_001307663;
	NP_001738
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Macrophage-capping protein (CAPG) also known as actin regulatory protein CAP-G is a protein that in humans is encoded by the CAPG gene.^[5]^[6]^[7]