Magnesium glycinate
Chemical compound
From Wikipedia, the free encyclopedia
Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycinate. The compound is sold as a dietary supplement.[1][2] It contains 14.1% elemental magnesium by mass.
| Names | |
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| IUPAC name
Magnesium diglycinate | |
| Systematic IUPAC name
Magnesium bis(aminoacetate) | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.035.305 |
| EC Number |
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C4H8MgN2O4 | |
| Molar mass | 172.423 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Magnesium glycinate is often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate[3] form.
Uses
Magnesium glycinate has been studied with applicability to patients with a bowel resection[1] or pregnancy-induced leg cramps.[2]
A 2013 systematic review suggested that higher dietary magnesium intake may be linked to reduced depression symptoms and that magnesium supplementation could help treat or prevent depression.[4]
The chelate bond with the amino acid glycine ensures above-average bioavailability, resulting in improved magnesium uptake. At the same time, gastrointestinal discomfort decreases significantly, making it particularly suitable for sensitive consumers in dietary supplements and medical foods.[5]

Chemical structure
According to X-ray crystallography, magnesium glycinate may exist in several forms, often with other anions.[6]
