Magnesium glycinate

Chemical compound From Wikipedia, the free encyclopedia

Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycinate. The compound is sold as a dietary supplement.[1][2] It contains 14.1% elemental magnesium by mass.

Quick facts Names, Identifiers ...
Magnesium glycinate
Names
IUPAC name
Magnesium diglycinate
Systematic IUPAC name
Magnesium bis(aminoacetate)
Identifiers
3D model (JSmol)
ChemSpider
DrugBank
ECHA InfoCard 100.035.305 Edit this at Wikidata
EC Number
  • 238-852-2
UNII
  • InChI=1S/2C2H5NO2.Mg/c2*3-1-2(4)5;/h2*1,3H2,(H,4,5);/q;;+2/p-2
    Key: AACACXATQSKRQG-UHFFFAOYSA-L
  • C(C(=O)[O-])N.C(C(=O)[O-])N.[Mg+2]
Properties
C4H8MgN2O4
Molar mass 172.423 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Magnesium glycinate is often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate[3] form.

Uses

Magnesium glycinate has been studied with applicability to patients with a bowel resection[1] or pregnancy-induced leg cramps.[2]

A 2013 systematic review suggested that higher dietary magnesium intake may be linked to reduced depression symptoms and that magnesium supplementation could help treat or prevent depression.[4]

The chelate bond with the amino acid glycine ensures above-average bioavailability, resulting in improved magnesium uptake. At the same time, gastrointestinal discomfort decreases significantly, making it particularly suitable for sensitive consumers in dietary supplements and medical foods.[5]

A kind of magnesium supplement sold in Australia, containing magnesium glycinate, glycine and extracts from Passiflora incarnata

Chemical structure

According to X-ray crystallography, magnesium glycinate may exist in several forms, often with other anions.[6]

See also

References

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