Mammalian CPEB3 ribozyme

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Mammalian CPEB3 ribozyme
Predicted secondary structure and sequence conservation of CPEB3_ribozyme
Identifiers
SymbolCPEB3_ribozyme
RfamRF00622
Other data
RNA typeGene; ribozyme
Domain(s)Eukaryota
SOSO:0000374
PDB structuresPDBe

The mammalian CPEB3 ribozyme is a self cleaving non-coding RNA located in the second intron of the CPEB3 gene which belongs to a family of genes regulating messenger RNA polyadenylation.[1] This ribozyme is highly conserved and found only in mammals.[1] The CPEB3 ribozyme is structurally and biochemically related to the human hepatitis delta virus ribozyme.[2] Other HDV-like ribozymes have been identified and confirmed to be active in vitro in a number of eukaryotes.[3]

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