Manchester score
System of assessing small-cell lung cancer
From Wikipedia, the free encyclopedia
Manchester score is an indicator of prognosis in small cell lung cancer.[1][2] It is calculated from a number of physical and biochemical markers.
A patient with small cell lung cancer scores one point for each of the following: [citation needed]-
- Serum lactate dehydrogenase exceeds the upper limit of the reference range.
- Serum sodium concentration less than 132 mmol/L.
- Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
- Serum bicarbonate less than 24.
- Karnofsky performance status less than 60.
- Extensive stage disease.
Prognosis
| Manchester score | Prognostic group | Two year survival (%) |
|---|---|---|
| 0-1 | Good | 16.2 |
| 2-3 | Medium | 2.5 |
| 4 or more | Poor | 0 |