Mannitol-1-phosphate 5-dehydrogenase
From Wikipedia, the free encyclopedia
In enzymology, a mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-mannitol 1-phosphate and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are fructose 6-phosphate, reduced NADH and a proton.[1][2][3][4]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannitol-1-phosphate:NAD+ 2-oxidoreductase. Other names in common use include hexose reductase, mannitol 1-phosphate dehydrogenase, D-mannitol-1-phosphate dehydrogenase, and fructose 6-phosphate reductase. This enzyme participates in fructose and mannose metabolism.
