Mannokinase
From Wikipedia, the free encyclopedia
Mannokinase (EC 2.7.1.7) is an enzyme that catalyzes the chemical reaction
| Mannokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.7 | ||||||||
| CAS no. | 9030-54-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme characterised from Schistosoma mansoni converts the hexose sugar, L-mannose (shown in its cyclic form) to L-mannose 6-phosphate by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).[1]
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-mannose 6-phosphotransferase. Other names in common use include mannokinase (phosphorylating), and D-fructose (D-mannose) kinase.[2]
