Map44

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Mannose-binding lectin-associated protein of 44 kDa (MAp44) is a protein arising from the human MASP1 gene. MASP-1, MASP-3 and MAp44 are alternative splice products of the MASP1 gene. MAp44 has been suggested to act as a competitive inhibitor of lectin pathway activation, by displacing MASP-2 from MBL, hence preventing cleavage of C4 and C2 [1]

SymbolMASP1
Alt. symbolsCRARF, PRSS5
Quick facts mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor), Identifiers ...
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Identifiers
SymbolMASP1
Alt. symbolsCRARF, PRSS5
NCBI gene5648
HGNC6901
OMIM600521
RefSeqNM_001879
UniProtP48740
Other data
LocusChr. 3 q27-q28
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StructuresSwiss-model
DomainsInterPro
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