In 2001 Stern began her academic career as a faculty member in the department of preventive medicine at the Keck School of Medicine of USC at the University of Southern California (USC).[2] Her early work focused on cancer epidemiology, and she developed an interest in understanding cancer disparities among minority populations.[3] Trained in cancer biology and population sciences, she explores the environmental and genetic risk factors for cancer, with a particular emphasis on dietary exposures and their potential role in cancer risk.[3]
In 2016, Stern expanded her role at USC by joining the department of urology, bridging preventive medicine and clinical research.[2] Her research includes clinical epidemiological studies that address disparities in cancer outcomes for minority groups, especially among Latino and Black populations.[3] She collaborates extensively with the Los Angeles Cancer Surveillance Program to examine cancer patterns in these communities.[2]
Stern is the associate director for population sciences at the USC Norris Comprehensive Cancer Center (NCCC) and serves as the Ira Goodman Chair in Cancer Research.[2] Stern plays a role in national initiatives aimed at improving cancer research and health equity.[2] She is the co-director and co-principal investigator for the Florida-California Cancer Research, Education, and Engagement (CaRE2) Health Equity Center.[2] This program, funded by the National Cancer Institute (NCI), fosters partnerships between USC, the University of Florida, and Florida A&M University to address cancer disparities.[2]
Stern is a member of the American Association for Cancer Research (AACR), where she serves on the minorities in cancer research council.[2] Her publications cover a wide range of topics in cancer epidemiology, including the role of diet in cancer risk, genetic risk factors, and prostate and colorectal cancer disparities.[3] Stern mentors the next generation of minority researchers, particularly through her involvement in education and training programs like CaRE2's summer cancer research education and training program.[2]