Loeffler has published research on the cultural history of Wales from the eighteenth to the twentieth centuries, concentrating on the development of political concepts in Britain and their expressions in Welsh, knowledge exchanges by cultural adaptation, and how Wales was linked into a wider scholarly community by international diplomats and scholars, and but also with the British Empire. Her project 'Knowledge Transfer and Social Networks: European Learning and the Revolution in Welsh Victorian Scholarship' (2014–2016)' was funded by the Leverhulme Trust.[2][3][4] It explored the life, times and European connections of the historian and social reformer Thomas Stephens of Merthyr Tydfil.
Loeffler is Assistant Editor of the Dictionary of Welsh Biography, where she aims to increase the number of entries on women and written by women. She contributes regularly to media platforms such as The Conversation and the BBC.[5][6] One of her heroes is the Egyptologist Käthe Bosse-Griffiths.[7]
