Longfellow was active throughout her life in the art communities of Boston and Portland, Maine. On several occasions she toured Europe, Mexico, and the American South in the company of friends and family members such as aunt Alice Mary Longfellow, sister Lucia Wadsworth Longfellow Barrett, brother Alexander Wadsworth Longfellow Jr., or lifelong friend and fellow artist Catherine Talbot. Longfellow's other interests included photography, sailing, shooting, sewing, writing poetry, and performing on stage. She kept a lifelong diary.[1][2]
Longfellow was a lifelong resident of Portland and died at home there on September 17, 1945, at the age of 92. She was buried at the Evergreen Cemetery in Portland. She was the closest surviving relative of Henry Wadsworth Longfellow at the time of her death.[1]