Matrona was born in Perge about 424.[2] Pious and charitable, she was married to Domitianus. They had one daughter.[3] She persuaded Domitianus to move to Constantinople, where she would visit the churches. When she would attend night vigils, her jealous and suspicious husband accused her being a prostitute. Wishing to lead an ascetic life, she abandoned her home and stayed with an acquaintance, Susanna, to whom she entrusted her daughter.
Afraid her husband would find her, she cut her hair, dressed in men's clothes, and presented herself at the monastery of St. Bassianus as a eunuch named Babylos. The monks received her and she became a member of the community, and was set to work in the garden.[4] After about three years, Bassianus realized the ruse and Matrona returned temporarily to Susanna. But as her husband continued to search for her Bassianus suggested that she go to a woman's monastery in Emesa, where she eventually became abbess. She became famous for her miraculous gift of healing. Her husband subsequently found her and followed her to Jerusalem, Syria, and Beirut, where she lived as an ascetic in an ancient pagan temple.[5]
When Bassianus learned of this he decided to establish a small monastery for Matrona and others not far from his own. The nuns under the leadership of Matrona were granted a unique privilege by Bassianus, "He did not give her woolen girdles and veils such as women were accustomed to wear, but men's wide black leather belts and men's white mantles. And these they wore continuously".
She is known for opposing the Monophysite policy of the emperor Anastasios I. St. Matrona died at the age of 100, around the year 524.[2]
Her life was told through a vita prima whose author and exact time period remains a mystery.[6] Hippolyte Delehaye thought the text to be of dubious value.[3]
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