Metchnikowin
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| Metchnikowin | |
|---|---|
 The fruit fly, Drosophila melanogaster | |
| Identifiers | |
| Symbol | Metchnikowin, Mtk |
| InterPro | IPR012513 |
Metchnikowin is a 26-residue antimicrobial peptide of the fruit fly Drosophila melanogaster that displays both antibacterial and antifungal properties.[1] This peptide is expressed strongly in the Drosophila fat body (an organ similar to the human liver), but is also expressed at surface epithelia in the trachea and gut. This is regulated by the NF-κB signalling pathways Toll and Imd.[2] Metchnikowin is named after Russian immunologist Élie Metchnikoff, one of the founders of modern immunology.