Methyl acetate hydrolase
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| Methyl acetate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Collage of methyl acetate hydrolases from various bacterium, from clockwise: Gordonia sp., Nocardioides perillae, Rhodospira trueperi, Calidifontibacter indicus. | |||||||||
| Identifiers | |||||||||
| EC no. | 3.1.1.114 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Methyl acetate hydrolase, known also as methylacetate acetohydrolase is a hydrolase enzyme that utilizes H2O to carry out the hydrolysis of methyl acetate (CH3COOCH3), a weakly lipophillic and polar compound used often as a solvent. In the species Gordonia sp. (strain TY-5), the enzyme is encoded by gene acMB.[1] The enzyme catalyzes the following reaction,
- methyl acetate + H2O = methanol + acetate + H+
The enzyme is involved in two major pathways, the butanoate metabolism pathway and the catabolic degradation pathway of propanol.[2][3][4]