Methyl acetoacetate

Methyl acetoacetate
Names
	IUPAC name methyl 3-oxobutanoate
	Other names Acetoacetic acid methyl ester; Methyl acetylacetate; 3-Oxobutanoic acid methyl ester;
Identifiers
CAS Number	105-45-3 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:166454;
ChEMBL	ChEMBL3186053;
ChemSpider	13874867 ;
ECHA InfoCard	100.003.000
EC Number	203-299-8;
PubChem CID	7757;
UNII	CW4I82QAX1;
UN number	1993
CompTox Dashboard (EPA)	DTXSID9026716 ;
	InChI InChI=1S/C5H8O3/c1-4(6)3-5(7)8-2/h3H2,1-2H3 Key: WRQNANDWMGAFTP-UHFFFAOYSA-N ;
	SMILES COC(=O)CC(C)=O;
Properties
Chemical formula	C5H8O3
Molar mass	116.116 g·mol−1
Appearance	Colourless liquid
Odor	Fruit or rum
Density	1.076 g/cm3
Boiling point	166 °C (331 °F; 439 K)
Solubility in water	40 g/100 mL (20 °C)
Refractive index (nD)	1.411
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305+P351+P338
NFPA 704 (fire diamond)	2 2
Flash point	70 °C (158 °F; 343 K)
Related compounds
Related esters	Ethyl acetoacetate; Ethyl acetate; Diethyl malonate;
Related compounds	Acetone; Acetylacetone; Diketene;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

The organic compound methyl acetoacetate is the methyl ester of acetoacetic acid. It is a colorless liquid. It is used as a chemical intermediate. Many of its properties are similar to those for ethyl acetoacetate, which is more common.

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At large scale, methyl acetoacetate is industrially produced by treatment of diketene with methanol.^[2]

Safety and environmental considerations